2010

GUI To Facilitate Research on Biological Damage From Radiation

A graphical-user-interface (GUI) computer program has been developed to facilitate research on the damage caused by highly energetic particles and photons impinging on living organisms. The program brings together, into one computational workspace, computer codes that have been developed over the years, plus codes that will be developed during the foreseeable future, to address diverse aspects of radiation damage. These include codes that implement radiation-track models, codes for biophysical models of breakage of deoxyribonucleic acid (DNA) by radiation, pattern-recognition programs for extracting quantitative information from biological assays, and image-processing programs that aid visualization of DNA breaks.

The radiation-track models are based on transport models of interactions of radiation with matter and solution of the Boltzmann transport equation by use of both theoretical and numerical models. The biophysical models of breakage of DNA by radiation include biopolymer coarse-grained and atomistic models of DNA, stochastic-process models of deposition of energy, and Markov-based probabilistic models of placement of doublestrand breaks in DNA. The program is designed for use in the NT, 95, 98, 2000, ME, and XP variants of the Windows operating system.

This program was written by Frances A. Cucinotta of Johnson Space Center and Artem Lvovich Ponomarev of Universities Space Research Association. For more information, download the Technical Support Package (free white paper) at www.techbriefs.com/tsp under the Bio-Medical category.

Universities Space Research Association has requested permission to assert copyright for the software code. MSC-23853-1

This Brief includes a Technical Support Package (TSP).

GUI To Facilitate Research on Biological Damage From Radiation (reference MSC-23853-1) is currently available for download from the TSP library.

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