Semrock (Rochester, NY) has released four new optical filter sets for fluorescence imaging which enable the choice of substantially increased brightness or enhanced contrast when imaging the fluorescent labels fluorescein (FITC) and green fluorescent protein (GFP). These new BrightLine® filter sets allow the user to either minimize photo-bleaching while increasing image contrast, or receive a light boost for a noticeably brighter image, particularly in low-concentration applications such as single-molecule imaging. The single-band filter sets GFP-1828-A and FITC-2024-A offer the highest contrast of filter sets available today, while the GFP-4050-A and FITC-5050-A sets give the user the highest brightness among sets optimized for these fluorophores. Photonics West Booth #616

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