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Making Mesh Buckypaper Capsules for Transplantation of Cells and Implantation of Medical Devices

Applications include gene therapy, cell transplantation for treatment of diabetes and other disorders, and improved biocompatibility of implantable medical devices. Ames Research Center, Moffett Field, California The innovation consists of a method for fabricating containers (“biocapsules”) made of biocompatible mesh for holding living cells and tissues, to facilitate transplantation into the body, for a wide range of high-impact medical applications. The biocompatible mesh (buckypaper) is made of carbon nanotubes (CNTs), and the containers are fabricated by depositing the nanotubes onto pre-formed molds, in order to achieve the desired shape and size of the biocapsule. Various forms are possible, including hollow tubes, closed cylinders, and more complex shapes, determined by the configuration of the mold. The biocompatibility of the capsule makes it possible to implant a variety of cells into a host, even cells that would otherwise be considered “foreign,” such as cells from unmatched donors, specially engineered cells, and even nonhuman cells. Because the capsule pores are too small for the cells to pass, the cells stay inside the capsule, where they are protected from the host immune system. The pores of the biocapsule permit gas exchange (oxygen, carbon dioxide), as well as free diffusion of metabolites, which keeps the cells healthy. Tissue or tissue fragments, and micro- or nano-scale medical devices can also be placed inside the biocapsule to facilitate their implantation into the body.

Posted in: Medical, Briefs

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Non-Binary Protograph-Based LDPC Codes for Short Block Lengths

The constrained protograph-based LDPC codes are a new class of codes proposed for low-complexity implementation of decoders. NASA’s Jet Propulsion Laboratory, Pasadena, California Short block codes are in demand by international space agencies for transmission of command and control data to spacecraft in the uplink channel. Codes that outperform currently used binary codes with the same block lengths and code rates are desirable. A design method constructs non-binary LDPC (low-density parity-check) codes both for unconstrained non-binary protograph-based codes and the new class of constrained protograph-based codes. The non-binary short block codes outperform the binary version by at least 1 dB for the same block size and code rate.

Posted in: Information Sciences, Electronics & Computers, Briefs

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Method Resolves Algebraic Loops While Improving Accuracy and Reducing Runtime

Higher accuracies are achieved while running at the lower base sample rate. Armstrong Flight Research Center, Edwards, California A method has been developed for resolving algebraic loops that occur in closed-loop systems when using MathWorks Simulink modeling and simulation tools. This variable fidelity method improves accuracy and reduces runtime significantly for users of Simulink Coder applications. The method improves the Simulink Coder tool’s ability to more efficiently and quickly generate C code based on algorithms modeled in the simulation tool. By replacing transfer functions that require high sampling rates with embedded function integration schemes, users can achieve continuous transfer function accuracy at almost no computational cost. The innovation also enables computationally intensive block diagrams to run faster in real time, and satisfies Nyquist frequency requirements in models. Algebraic loops are resolved through fast sampling, making the innovation especially applicable to high-speed systems with saturation limits, dead-bands, and other constraints that create fast dynamics.

Posted in: Information Sciences, Electronics & Computers, Briefs

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The Next Mars Journey

The next rover NASA will send to Mars in 2020 will carry seven instruments to conduct unprecedented science and exploration technology investigations on the Red Planet. The instruments were selected recently from 58 proposals from researchers and engineers worldwide. The Mars 2020 mission will be based on the design of the Mars Science Laboratory rover, Curiosity.

Posted in: UpFront

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Product of the Month: September 2014

Dewetron, Wakefield, RI, has introduced the TrendCorder series of instruments designed for basic data acquisition applications in industry. They feature intuitive, multi-touch operation, enabling them to be operated 100% by touch, including alphanumeric entry, channel setup, and display configuration. When the instrument is turned on, an app loads and shows incoming data immediately. The DejaVIEW™ feature enables a user to scroll back on the recorder graph to any place in the recording, and pinch/zoom on the graph to see any detail, no matter how far back in time, without interrupting current recording. This is designed for operators conducting long-term testing that cannot be interrupted. The instruments feature a 15.4" wide aspect multi-touch display, and data is streamed continuously to disk at rates up to 200 MB/s. The TrendCorder has four slots for TRION series plug-in modules. Three 6-channel modules are included in the TRC-18, with one slot free; the TRC-6 has one 6-channel module, with three slots free. The system weighs 18.7 pounds, including the input modules.

Posted in: Products

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Unique Camera Gauge System Controls Spring Manufacturing

Efficient and accurate operations are vital to the success of today’s manufacturer. Newcomb Spring, a manufacturer of custom springs, wire forms and stampings, is continually working to improve their production processes. The company has also seen an increasing number of requests for reports that detail the compliance of completed orders. Newcomb’s in-house Research and Development (R&D) Department is tasked with developing and building new technologies and equipment to solve unique challenges as well as improve overall operations and efficiency. Recently, Newcomb Spring introduced its own camera gauge system, developed by its R&D team, which was designed to provide high-speed manufacturing with automatic adjustments, extremely high levels of compliance, and reportable accuracy unmatched in the industry.

Posted in: Features, Photonics, Articles

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Securing and Validating Critical Vision Data

Manufacturing companies are placing increasing emphasis on data security throughout their operations to protect confidential data and to validate that their systems are protected against unauthorized and unwanted changes. The critical role that vision plays in many manufacturing processes makes it essential that system security be improved for vision applications. A new generation of vision-specific security tools offers improvements in access control, change tracking, auditing, and general network security to help ensure the integrity of vision applications while at the same time protecting data confidentiality.

Posted in: Applications, Photonics, Application Briefs

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