Replaceable Microfluidic Cartridges for a PCR Biosensor
Lyndon B. Johnson Space Center, Houston, Texas
Friday, April 01 2005
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Design has been optimized for detection of target DNA sequences
The figure depicts a replaceable microfluidic cartridge that is a component of a miniature biosensor that detects target deoxyribonucleic acid (DNA) sequences. The biosensor utilizes (1) polymerase chain reactions (PCRs) to multiply the amount of DNA to be detected, (2) fluorogenic polynucleotide probe chemicals for labeling the target DNA sequences, and (3) a high-sensitivity epifluorescence-detection optoelectronic subsystem.
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