Progress in developing improved semiconductor lasers with emission in the mid-IR spectral region (≈3 μm to ≈15 μm) has depended heavily on the use of nanometer-scaled structures. Mid-IR quantum cascade lasers (QCLs), for example, represent a “tour de force” of semiconductor nanotechnology where large band gap GaAs and InP based III-V semiconductor multiple quantum well (MQW) structures are used to engineer intersubband transition energies that enable mid-IR photon emission. First developed at Bell Labs and now demonstrated by many other groups, QCLs have offered great hope as a new mid-IR light source for applications such as trace gas sensing  and isotope ratio measurement . However, from their first use , QCL operation has been complicated by high power inputs, typically a minimum of 5 watts, and associated high heat load in packaged systems. Considering the significant resources devoted to QCL development and the apparent lack of progress in reducing high power consumption levels over the last ten years, it is likely that this problem is fundamental to QCL design. QCLs require high applied voltages (>8 volts) to achieve the necessary band alignment and the cascade effect, so focusing on this contribution is not expected to be fruitful. The other contribution, high threshold current (≈300 mA), appears to be fundamental to all intersubband lasers where there are parallel energy versus momentum dispersion relationships for electrons associated with intraband laser transitions. Figure 1, which depicts E vs. k subband dispersion for a three-level QCL gain medium, shows that there is an efficient competing non-radiative relaxation pathway for excited electrons when they scatter with non-zone-center optical or acoustic phonons. Since low energy subband separation is required for mid-IR light emission and the sub-band dispersions are parallel, such electron-phonon scattering will always be an efficient upper laser state depopulation mechanism thus necessitating high electron currents to achieve population inversion. Note, as indicated in Figure 1, the deliberate use of electron-phonon resonance with longitudinal optical (LO) phonons in QCL designs to depopulate the lower laser transition subband states. Exploitation of such electrophonon resonance effects in reducing laser threshold currents will be discussed below within the context of interband IV-VI mid-IR lasers.
A second cascade laser approach, pioneered by Rui Yang  and recently replicated at the Naval Research Laboratory , involves use of narrow band gap GaSb based heterostructures that employ a type II band alignment. In this case, lasing involves interband transitions between quantum confined conduction and valence subband states such that low energy mid-IR photons are generated. These lasers can benefit from the same cascade effect as QCLs, but since the lasing transitions are interband the subband dispersions for the relevant laser transition states are not parallel, and this helps to reduce significantly upper laser transition state depopulation effects associated with electron-phonon scattering. Low interband cascade laser (ICL) threshold currents of less than 20 mA (8 A/cm2) at 80 K , which are significantly smaller than those for QCLs, (e.g. 225 mA (400 A/cm2) at 80 K ), provide strong evidence for the negative impact that electron-phonon scattering can have on semiconductor lasers that utilize intraband transitions. It can thus be argued that interband mid-IR lasers have inherent advantages over QCL-type intraband mid-IR lasers.