A client seeks new synthetic (chemical-based) control agents for insects such as aphids and spider mites. The piercing and sucking insects damage plants by inserting their mouthpart into plant tissues and feeding on the juices. Heavily infested plants become yellow, wilted, deformed, or stunted, and may eventually die. There is a need to pursue insect control agents with new modes of action in order to keep insecticide resistance at manageable levels. The proposed insect control agents must be systemic, broad-spectrum insecticides that have low risk to humans and the environment.