An inorganic, biodegradable silica gel fiber (SGF) acts as a physical scaffold to aid the growth of new cells and the collagen structure that supports them. As a scaffold, it can also be used to deliver drugs over a wide area to aid in healing. The material is integrated into the tissues and resorbed by the body. Unlike collagen, the SGF scaffold stays in the wound for 1–2 weeks before resorption. Dimension as well as degradation speed can be adjusted from millimeters up to several hundred square centimeters.SGF promotes active growth of different cell types, including fibroblasts, keratinocytes, osteoblasts, and chondrocytes. For tissue regeneration, SGF works with hard and soft tissues, and promotes bone and cartilage regeneration.