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Multi-Parameter Biodosimetric HemoDose Tools

Lyndon B. Johnson Space Center, Houston, Texas There are continuous concerns about the possibility of nuclear and radiological terrorism or accidents that may result in mass casualties in densely populated areas. To guide medical personnel in their clinical decisions for effective medical management and treatment of exposed individuals, biomarkers are usually applied to examine radiation-induced biological changes to assess the severity of radiation injury. Among these, peripheral blood cell counts are traditionally regarded as the most practical and rapid diagnostic indicators.

Posted in: Briefs, Medical

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Soft-Tissue Emulsification Using a Mechanism of Ultrasonic Atomization Inside Gas or Vapor Cavities

Lyndon B. Johnson Space Center, Houston, Texas The current method of emulsifying tissue employs focused ultrasound with microsecond pulses and cavitation. This invention emulsifies soft tissue using a mechanism of ultrasonic atomization inside gas or vapor cavities. The method of non-invasively treating tissue includes pulsing ultrasound energy from the ultrasound source toward the target site in the tissue. The ultrasound source is configured to emit high-intensity focused ultrasound (HIFU) waves. The target site comprises a pressure-release interface of a gas or vapor cavity located within the tissue. The method continues by generating shock waves in the tissue to induce a lesion at the target site. It additionally includes characterizing the lesion based on a degree of at least one of a mechanical or thermal ablation of the tissue. This work was done by Oleg Sapozhnikov, Michael Bailey, Tatiana Khokholova, Vera Khokholova, and Julianna Simon of the University of Washington for Johnson Space Center. NASA is seeking partners to further develop this technology through joint cooperative research and development. For more information about this technology and to explore opportunities, please contact jsc-techtran@mail.nasa.gov. MSC-25191-1

Posted in: Briefs, Medical

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5 Ways the Automated Compliance Management System Provides Value for Your Organization

When looking for a Compliance Management system that is ideal for your organization, there is a lot to take into consideration - with so many options out there it becomes difficult to choose the system that will provide the most value.

Posted in: MDB, White Papers, White Papers, Bio-Medical, Medical

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Low Friction Plastic Technology For Single-use Drug Delivery Devices

Start-up coefficient of friction and stick-slip (or “stiction”) elimination are dominant performance drivers in single-use drug delivery devices that have moving parts. RTP Company has completed a rigorous investigation that establishes and defines a new friction test to measure and compare plastic-against-plastic friction behavior that occurs at initial startup. This new test uses forces and speeds that characterize the action of injection pens, auto-injectors, stop cocks, inhalers, safety syringes and other devices. This paper describes the newly created friction test method, and its core data point known as Glide FactorSM, as well a series of tests to compare the friction behavior of select polymers and internal lubricants for use in single-use drug delivery devices. The use of internally lubricated plastics can eliminate costly secondary operations to apply a topical lubricant, reduce the total amount of silicone that reaches the patient via the device, and improve the overall quality of the device. The goal of this paper is to share a tribological database that enables device designers to screen plastic-on-plastic friction pairs to optimize safe and effective material selections.

Posted in: MDB, White Papers, White Papers, Coatings & Adhesives, Materials, Medical

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How to Prevent Step Losses with Stepper Motors

While stepper motors are an excellent solution for many applications, a key concern is step losses. However, in most instances step losses can be prevented or corrected. It is important to remember that a stepper motor does not operate like a DC motor. This white paper from MICROMO engineers provides guidance to determine step losses or non-operation across a variety of applications.

Posted in: White Papers, White Papers, Mechanical Components, Medical, Motion Control, Motors & Drives

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Optimizing Electronics for Medical Applications

Two years ago, in Medical Design Briefs, Derek Hunt offered some insight into the benefits of Complementary Metal-Oxide Semiconductor (CMOS) technology in the miniaturization of medical devices. CMOS has been around for decades and aside from the size benefits which will be discussed shortly, the technology also brings significant cost savings and performance improvements to the medical world. Readers who are currently engaged in the design of medical electronics already recognize this. It’s actually difficult to design such products today without incorporating CMOS devices. And because medical devices often contain many analog components, there remains one critical decision point designers must address and that is whether to design with standard off-the-shelf standard analog products or engage with a semiconductor company to produce a custom analog chip for the application.

Posted in: Features, Medical

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Making the Compliance Grade: Quantitative View on Compliance Management

Whether building enterprise-level solutions, using cloud-based solutions, or even building in-house solutions, the dynamic of automation is a key component in the compliance market. VERSE gauged the common challenges in compliance around Quality and Safety and compiled the results in this compliance grader white paper.

Posted in: White Papers, White Papers, Medical

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