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Chemical Analysis without Reagents Print E-mail
Roche   
Oct 31 2007
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A portfolio of technologies applies mid-infrared spectroscopy to the analysis of fluids. Any fluid can be analyzed, including blood, serum, and other biological fluids. Tests are non-destructive. The techniques require no reagents or other chemicals, and thus there are no chemicals to store or dispose of. The spectroscopic signatures obtained from the samples can be used to aid the diagnosis of disease, among other applications, because molecular signatures are unique. The technique has a high sensitivity to the conformation of the molecule: shape, folding, symmetry, and its state.

A key to the technology is proper sample preparation and drying. This is because water strongly absorbs mid-IR light. This technology includes optimized procedures for drying samples that can be automated. Multiple analytes can be obtained from one sample within a single measurement. Typical tests require only 30 seconds.

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