Imaging

Product of the Month: LED Light Engines for Large FOV Fluorescence Imaging Systems

Innovations in Optics, Inc. (Woburn, MA) offers high power LED Light Engines as excitation illuminators for large field-of-view fluorescent imagers used in life science instruments. LumiBright LE Light Engines feature patented non-imaging optics that direct LED light into a desired cone angle, while producing highly uniform output, both angularly and spatially. The two standard far-field half-angles are 20 and 40 degrees. Available peak LED wavelengths range from 365 nm in the ultraviolet through 970 nm in the near-infrared.

Posted in: Products, Products, LEDs, Photonics

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CCD Image Sensor

The KAI-08051 charge-coupled device (CCD) image sensor from ON Semiconductor (Phoenix, AZ) shares the same advanced 5.5 micron pixel architecture, 8 megapixel resolution, 15 frame per second readout rate, and 4/3 optical format as the existing KAI-08050 Image Sensor, but improves key performance parameters through the use of an improved amplifier design, newly optimized microlens structure, and new color filter pigments in both Bayer and Sparse color configurations.

Posted in: Products, Products, Photonics, Sensors

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Thermal Imaging Core

FLIR Systems, Inc. (Portland, OR) has announced its latest thermal imaging core, Muon™, which is designed specifically for OEMs capable of integrating uncooled FPAs into their own camera solutions. Muon is based on FLIR’s 17μ pitch Vandium Oxide (VOx) 640x512 or 336x256 FPAs and offers frame rates of 9Hz and up to 60Hz. Optimized for size, weight and power (SWaP), Muon has a form factor of 22 mm × 22 mm × 6 mm, a mass of less than 5 grams, and depending on the configuration, uses less than 300mW of power.

Posted in: Products, Products, Photonics

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Imaging Sensor Targets

Headwall (Fitchburg, MA) has announced the availability of a new hyperspectral imager targeting very high resolution spectral measurements of 0.1 nm over specific spectral ranges that yield indicators of vegetative fluorescence to measure plant health. The new sensor is based on Headwall's all-reflective concentric optical design that uses very precise, very high diffraction-efficiency gratings for simultaneous high spatial and spectral resolution of < 0.1nm across the spectral range of the instrument.

Posted in: Products, Products, Photonics, Sensors

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sCMOS Camera

The Andor (Belfast, UK) Neo 5.5 megapixel sCMOS camera is a unique - 40°C vacuum cooled platform designed around a low noise 5.5 megapixel sensor with 6.5 μm pixels and a 22mm diameter to drive lowest possible dark noise. Ideal for cell microscopy, astronomy, digital pathology, and high content screening, the Neo 5.5 delivers 30 fps sustained or up to 100 fps burst mode to its internal 4GB memory. The Rolling and Global shutter feature further enhances application flexibility, Global shutter in particular offering an ideal means to simply and efficiently synchronize the Neo with other 'moving' devices such as stages or light switching sources and eliminating the possibility of spatial distortion when imaging fast moving objects.

Posted in: Products, Products, Cameras, Photonics

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High-Speed Cameras

XIMEA (Munster, Germany) recently announced new Thunderbolt™ technology ready cameras that are equipped with the newest sensors from Sony (IMX174) and CMOSIS (CMV20000). The cameras provide highest speeds and direct access to computer memory at 10 and 20 Gbit/s respectively.

Posted in: Products, Products, Cameras, Photonics

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NASA Advances Next-Generation 3D-Imaging Lidar

Building, fixing, and refueling space-based assets or rendezvousing with a comet or asteroid will require a robotic vehicle and a super-precise, high-resolution 3D imaging lidar that will generate real-time images needed to guide the vehicle to a target traveling at thousands of miles per hour. A team at NASA’s Goddard Space Flight Center is developing a next-generation 3D scanning lidar — dubbed the Goddard Reconfiguable Solid-state Scanning Lidar (GRSSLi) — that could provide the imagery needed to execute these orbital dances. GRSSLi is a small, low-cost, low-weight platform capable of centimeter-level resolution over a range of distances, from meters to kilometers. Equipped with a low-power, eye-safe laser; a MEMS scanner; and a single photodetector, GRSSLi will "paint" a scene with the scanning laser, and its detector will sense the reflected light to create a high-resolution 3D image at kilometer distances. A non-scanning version of GRSSLi would be ideal for close approaches to asteroids. It would employ a flash lidar, which doesn’t paint a scene with a mechanical scanner, but rather illuminates the target with a single pulse of laser light — much like a camera flash. Source:

Posted in: News, Lasers & Laser Systems, Photonics, Machinery & Automation, Robotics

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Moving Cameras “Talk” to Identify and Track Pedestrians

University of Washington electrical engineers have developed a way to automatically track people across moving and still cameras by using an algorithm that trains the networked cameras to learn one another’s differences. The cameras first identify a person in a video frame then follow that same person across multiple camera views. With the new technology, a car with a mounted camera could take video of a scene, then identify and track humans and overlay them into the virtual 3D map on a GPS screen. The researchers are developing this to work in real time, which could help track a specific person who is dodging the police. The team also installed the tracking system on cameras placed inside a robot and a flying drone, allowing the robot and drone to follow a person, even when the instruments came across obstacles that blocked the person from view. Source:

Posted in: News, Cameras, Video, Visualization Software, Machinery & Automation, Robotics

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Imaging Via Nanoparticles Could Monitor Cancer and Other Diseases

MIT chemists have developed new nanoparticles that can simultaneously perform magnetic resonance imaging (MRI) and fluorescent imaging in living animals. Such particles could help scientists to track specific molecules produced in the body, monitor a tumor’s environment, or determine whether drugs have successfully reached their targets. The researchers have demonstrated the use of the particles, which carry distinct sensors for fluorescence and MRI, to track vitamin C in mice. Wherever there is a high concentration of vitamin C, the particles show a strong fluorescent signal but little MRI contrast. If there is not much vitamin C, a stronger MRI signal is visible but fluorescence is very weak. The researchers are now working to enhance the signal differences that they get when the sensor encounters a target molecule such as vitamin C. They have also created nanoparticles carrying the fluorescent agent plus up to three different drugs. This allows them to track whether the nanoparticles are delivered to their targeted locations. These particles could also be used to evaluate the level of oxygen radicals in a patient’s tumor, which can reveal valuable information about how aggressive the tumor is. Source:

Posted in: News, Patient Monitoring

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Technique Enables Imaging of Transparent Organisms

Researchers at the RIKEN Quantitative Biology Center in Japan and the University of Tokyo have developed a method that combines tissue decolorization and light-sheet fluorescent microscopy to take extremely detailed images of the interior of individual organs and even entire organisms. The work allows scientists to make tissues and whole organisms transparent, and then image them at extremely precise, single-cell resolution. The method, called CUBIC (Clear, Unobstructed Brain Imaging Cocktails and Computational Analysis), was used to take images of mouse brains, hearts, lungs, kidneys, and livers, and then was attempted on infant and adult mice. In all cases, they could get clear tissues. The method could be used to study how embryos develop or how cancer and autoimmune diseases develop at the cellular level, leading to a deeper understanding of such diseases and perhaps to new therapeutic strategies. The group plans to allow for the rapid imaging of whole bodies of adult mice or larger samples such as human brains, and to apply this technology to further our understanding of autoimmune and psychiatric diseases. Source:

Posted in: News

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