Manufacturing & Prototyping

Solvent/Non-Solvent Sintering To Make Microsphere Scaffolds

A solvent/non-solvent sintering tech- nique has been devised for joining poly- meric microspheres to make porous matri- ces for use as drug-delivery devices or scaf- folds that could be seeded with cells for growing tissues. Unlike traditional sinter- ing at elevated temperature and pressure, this technique is practiced at room tem- perature and pressure and, therefore, does not cause thermal degradation of any drug, protein, or other biochemical with which the microspheres might be loaded to impart properties desired in a specific application. Also, properties of scaffolds made by this technique are more repro- ducible than are properties of comparable scaffolds made by traditional sintering.

Posted in: Manufacturing & Prototyping, Briefs

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Technology Eliminates the Need for Pre-Wetting Cartridge Filters

This ePTFE membrane remains hydrophilic even after exposure to steam autoclave cycles and corrosive chemicals.There has been a long-term need in the filtration industry — particularly for a variety of life science applications — to eliminate the need for pre-wetting cartridge filters with alcohol before sending them to customers. It is not only an expensive, time-consuming process, but it also increases the risk of bacterial contamination.

Posted in: Bio-Medical, Packaging, Manufacturing & Prototyping, Medical, Briefs, MDB

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Development of Position-Sensitive Magnetic Calorimeters for X-Ray Astronomy

These calorimeters can be used in x-ray metrology, materials microanalysis, and medical applications.Metallic magnetic calorimeters (MMC) are one of the most promising devices to provide very high energy resolution needed for future astronomical x-ray spectroscopy. MMC detectors can be built to large detector arrays having thousands of pixels. Position-sensitive magnetic (PoSM) microcalorimeters consist of multiple absorbers thermally coupled to one magnetic microcalorimeter. Each absorber element has a different thermal coupling to the MMC, resulting in a distribution of different pulse shapes and enabling position discrimination between the absorber elements. PoSMs therefore achieve the large focal plane area with fewer number of readout channels without compromising spatial sampling.

Posted in: Manufacturing & Prototyping, Briefs, TSP

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Cryogenic-Compatible Winchester Connector Mount and Retaining System for Composite Tubes

A connector retainer and mounting system has been designed to replace screw-mounting of Winchester connectors. Countersunk screws are normally used to secure connectors to structures, and to keep them from coming apart. These screws are normally put into threaded or through-holes in metallic structures. This unique retainer is designed such that integral posts keep the connector halves retained, and a groove permits a cable tie to be fastenedaround the retainer and composite tube, thus securing the connector to the structure.

Posted in: Manufacturing & Prototyping, Briefs, TSP

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Utilizing Machine Vision Engines for Advanced Quality Control and Object Detection

Advanced object and feature recognition eliminates the need for physical probing or fixed sensors.Incorporating machine vision engines into an OEM system with automated handling provides a wide range of benefits to the manufacturer. Machine vision engines are self-contained vision systems that include the optics, lighting, image sensor, electronics, and software to enable standalone “intelligent” decision-making using vision software. Machine vision engines are also much more compact than traditional industrial machine vision systems, which makes them more appropriate for integration into OEM systems with limited space.

Posted in: Bio-Medical, Imaging, Photonics, Manufacturing & Prototyping, Medical, Briefs, MDB

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Maintaining Sterility Assurance Level in Medical Device Design

To avoid costly interruptions later on, sterility assurance should be placed at the forefront of the design process.A medical device undergoing design and classified as sterile will be confronted with various obstacles, not the least of which is how to determine and maintain its proposed Sterility Assurance Level (SAL) as it approaches its ultimate goal: delivery to market.

Posted in: Bio-Medical, FDA Compliance/Regulatory Affairs, Manufacturing & Prototyping, Medical, Briefs, MDB

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Graphite Composite Panel Polishing Fixture

Composite fixture eliminates problems that may be caused by those made from aluminum.The use of high-strength, lightweight composites for the fixture is the novel feature of this innovation. The main advantage is the light weight and high stiffness-to-mass ratio relative to aluminum.

Posted in: Manufacturing & Prototyping, Briefs, TSP

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