Bioabsorbable Material Textile for Improving In Vivo Device Design

Created by a carding and needle-punch process, this non-woven structure is designed to create three-dimensional environments for cell proliferation and function. A non-woven absorbable scaffold has been designed for implant devices in orthopedics, cardiology, and general surgery, as well as other in vivo applications. Where classic tissue engineering utilized non-woven textile structures as environments for cell growth, medical device developers are now going further to exploit the benefits of these bioabsorbable scaffolds for applications and surgical procedures right inside the body, as well as for cosmetic surgery, wound care, and more. BIOFELT combines the benefits of traditional 3D non-woven scaffold technology with advanced manufacturing techniques to deliver this transformative capability.

Posted in: Bio-Medical, Materials, Implants & Prosthetics, Medical, Orthopedics, Briefs, MDB


Rotary Sensing Technologies for Medical and Robotic Shaft Angle Sensing Applications

This technical brief provides an overview of existing types of rotary sensor technologies, and compares the strengths and weaknesses of each type for use as through-hole shaft angle sensing devices. Today’s sensor technologies for robotic and medical applications include many devices that have evolved from industrial applications. Because of this general migration, they are not ideally suited to the requirements in new robotic and medical products. Specifically, conventional contacting and non-contacting sensing solutions do not offer the customization, small package size(s), and environmental and durability requirements that are so necessary in these custom applications.

Posted in: Bio-Medical, Positioning Equipment, Sensors, Medical, Robotics, Briefs, MDB


Functional Electrical Stimulation Technique May Improve Neural Implants

Researchers improve the efficiency of devices that stimulate damaged nerves, reducing potential side effects. Electrical implants that shut down excessive activity in brain cells hold great potential for treating epilepsy and chronic pain. Likewise, devices that enhance neurons’ activity may help restore function to people with nerve damage.

Posted in: Bio-Medical, Electronic Components, Rehabilitation & Physical Therapy, Implants & Prosthetics, Medical, Briefs, MDB


Monitoring Location and Angular Orientation of a Pill

System is part of targeted drug delivery. A mobile pill transmitter system moves through, or adjacent to, one or more organs in an animal or human body, while transmitting signals from its present location and/or present angular orientation. The system also provides signals from which the present roll angle of the pill, about a selected axis, can be determined. When the location coordinates angular orientation and the roll angle of the pill are within selected ranges, an aperture on the pill container releases a selected chemical into, or onto, the body. Optionally, the pill, as it moves, provides a sequence of visually perceptible images. The times for image formation may correspond to times at which the pill transmitter system location or image satisfies one of at least four criteria.

Posted in: Bio-Medical, Medical, Briefs, TSP


Molecular Technique to Reduce PCR Bias for Deeper Understanding of Microbial Diversity

This technique has applications in medical manufacturing, food processing, and municipal water treatment. Current planetary protection policies require that spacecraft targeted to sensitive solar system bodies be assembled and readied for launch in controlled cleanroom environments. A better understanding of the distribution and frequency at which high-risk contaminant microbes are encountered on spacecraft surfaces would significantly aid in assessing the threat of forward contamination. However, despite a growing understanding of the diverse microbial populations present in cleanrooms, less abundant microbial populations are probably not adequately taken into account due to technological limitations. This novel approach encompasses a wide spectrum of microbial species and will represent the true picture of spacecraft cleanroom-associated microbial diversity.

Posted in: Bio-Medical, Medical, Briefs, TSP


Improved Whole-Blood-Staining Device

Additional applications have been identified. Dramatic improvements have been made in NASA’s Whole Blood Staining Device (WBSD) since it was last described in “Whole-Blood- Staining Device,” NASA Tech Briefs, Vol. 23, No. 10 (October 1999), page 64. The new system has a longer shelf life, a simpler and more effective operational procedure, improved interface with instrumentation, and shorter processing time. More specifically, the improvements have targeted bag and locking clip materials, sampling ports, and air pocket prevention.

Posted in: Bio-Medical, Medical, Briefs


Magnetic Responsive Hydrogel Material Delivery System

Magnetic nanoparticles can be used as contrasting agents in MRIs, and as a drug delivery mechanism. Interest in the design of new drug delivery systems focuses on releasing the drug at a controlled rate and desired time. Magnetic nanoparticles (MNPs) have shown great potential for use in biomedicine due to their ability to get close to biological entities such as cells, viruses, proteins, and genes with heating ability when exposed to a time-varying magnetic field. Superparamagnetic MNPs with proven biocompatibility have attracted attention as drug carriers in hyperthermia therapy, magnetic resonance imaging (MRI) as a contrasting agent, tissue repair, immunoassay, and cell separation procedures.

Posted in: Bio-Medical, Medical, Drug Delivery & Fluid Handling, Nanotechnology, Briefs, MDB


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