Medical

FRET-Aptamer Assays for Bone Marker Assessment, C-Telopeptide, Creatinine, and Vitamin D

Applications include assessment of osteoporosis, and aptamer assays for veterinary analytes, infectious disease, food- and water-borne pathogens, and chemical/biological threats. Astronauts lose 1.0 to 1.5% of their bone mass per month on long-duration spaceflights. NASA wishes to monitor the bone loss onboard spacecraft to develop nutritional and exercise countermeasures, and make adjustments during long space missions. On Earth, the same technology could be used to monitor osteoporosis and its therapy.

Posted in: Bio-Medical, Medical, Briefs

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Medicine Delivery Device With Integrated Sterilization and Detection

This automated medicine delivery device would ensure that patients receive medication on schedule and at the right dosage level. Sterile delivery devices can be created by integrating a medicine delivery instrument with surfaces that are coated with germicidal and anti-fouling material. This requires that a large-surface- area template be developed within a constrained volume to ensure good contact between the delivered medicine and the germicidal material. Both of these can be integrated using JPLdeveloped silicon nanotip or cryo-etch black silicon technologies with atomic layer deposition (ALD) coating of specific germicidal layers.

Posted in: Bio-Medical, Medical, Briefs

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100 Percent Solids: Superior Adhesive Technology for the Medical Industry

Adhesives using 100 percent solids coating act fast, without need for solvents. In the medical industry, adhesives play a crucial role in applications ranging from diagnostics and device assembly to transdermal and wound care. There are varying methods by which an adhesive can be coated onto a substrate, but solvent coating has dominated in the medical industry for many years. Solvent-coated silicone, acrylic, and rubber-based adhesives are widely used as medical adhesive solutions. Despite their popularity, solvent-coated adhesives are far from a perfect answer to the medical market’s needs. Solvents may contain volatile organic compounds (VOCs) and even carcinogens that can be dangerous to humans. There are also major concerns regarding outgassing or leaching from solvent- coated adhesives in medical settings. As a process, solvent coating is not especially efficient with adhesives requiring drying, which can limit speed and cost-effectiveness of processing.

Posted in: Bio-Medical, Manufacturing & Prototyping, Materials / Adhesives / Coatings, Materials, Coatings & Adhesives, Medical, Briefs, MDB

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Humanlike Articulated Robotic Headform for Respirator Fit Testing

The testing of individual respiratory protection (IRP) devices is now accomplished with panels of human wearers. Historical attempts to simulate the human face and head have been unsuccessful for a variety of reasons that include imprecision in reproduction of facial dimensions and unrepresentative textures of the surfaces applied to headforms.

Posted in: Bio-Medical, Medical, Briefs, MDB

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Visual Image Sensor Organ Replacement

This innovation is a system that augments human vision through a technique called “Sensing Super-position” using a Visual Instrument Sensory Organ Replacement (VISOR) device. The VISOR device translates visual and other sensors (i.e., thermal) into sounds to enable very difficult sensing tasks.

Posted in: Bio-Medical, Software, Imaging & Diagnostics, Biosensors, Imaging, Displays/Monitors/HMIs, Sensors, Medical, Briefs, MDB

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Wireless Body Area Networks for Health Monitoring

A wireless personal health monitoring system using smartphones to upload data could revolutionize US healthcare. Faculty in the departments of electrical and computer engineering are leading research in mHealth at The University of Alabama in Huntsville. mHealth capitalizes on what Dr. Emil Jovanov, associate dean for graduate education and research in the College of Engineering, calls “major revolutions” in computer informatics, smartphones, and energy-efficient and miniaturized electronics and sensors. It can provide health information to the patient directly, to the physician via the Internet, and to researchers as aggregated databases.

Posted in: Bio-Medical, Software, Imaging & Diagnostics, FDA Compliance/Regulatory Affairs, Electronics, Medical, Diagnostics, Briefs, MDB

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Integrating Force Sensors into Robotic Surgery

Force sensing resistors provide tactile feedback during robotic surgery. Due to advances in electronics and technology, robotic surgery has become increasingly popular. Surgeons no longer have to operate directly on a patient, but instead can control a robot to carry out the procedure. Robotic surgery has benefits to both the surgeon and the patient. For the surgeon, robots display 3D visualization for enhanced viewing of the operative area and improve the control, precision, and range of motion of smaller instruments. While robotic surgery may seem like the future of the medical industry, it still has obstacles to overcome. One significant disadvantage to robotic surgery is the lack of haptic technology, which provides physical sensations that enable electronics to give their users force feedback.

Posted in: Bio-Medical, Manufacturing & Prototyping, Surgical Robotics/Instruments, Biosensors, Sensors, Medical, Briefs, MDB

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