Medical

Portable Intravenous Fluid Production Device for Ground Use

This small, portable device with high output produces medical injection-grade sterile water from potable water sources. There are several medical conditions that require intravenous (IV) fluids. Limitations of mass, volume, storage space, shelf-life, transportation, and local resources can restrict the availability of such important fluids. These limitations are expected in long-duration space exploration missions and in remote or austere environments on Earth. Current IV fluid production requires large factory-based processes. Easy, portable, on-site production of IV fluids can eliminate these limitations. Based on experience gained in developing a device for spaceflight, a grounduse device was developed.

Posted in: Bio-Medical, Medical, Briefs

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Adaptation of a Filter Assembly to Assess Microbial Bioburden of Pressurant Within a Propulsion System

A report describes an adaptation of a filter assembly to enable it to be used to filter out microorganisms from a propulsion system. The filter assembly has previously been used for particulates >2 μm. Projects that utilize large volumes of nonmetallic materials of planetary protection concern pose a challenge to their bioburden budget, as a conservative specification value of 30 spores/cm3 is typically used.

Posted in: Bio-Medical, Medical, Briefs, TSP

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PMA-Linked Fluorescence for Rapid Detection of Viable Bacterial Endospores

This method has applications in the pharmaceutical, food microbiology, semiconductor, and other industries requiring surface sterilization. The most common approach for assessing the abundance of viable bacterial endospores is the culture-based plating method. However, culture-based approaches are heavily biased and oftentimes incompatible with upstream sample processing strategies, which make viable cells/spores uncultivable. This shortcoming highlights the need for rapid molecular diagnostic tools to assess more accurately the abundance of viable spacecraft-associated microbiota, perhaps most importantly bacterial endospores.

Posted in: Bio-Medical, Medical, Briefs

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Pre-Validated Medical Packaging Solution

This approach helps OEMs improve the process of getting a product into a validated sterile barrier system. Due to the complex requirements of the medical device industry, the internal resources of device OEMs are drawn primarily to the device R&D and regulatory arenas. However, once the device R&D is complete, there is still a major hurdle left to tackle: how to get a product into a validated sterile barrier system.

Posted in: Bio-Medical, Manufacturing & Prototyping, Custom & Contract Manufacturing, Packaging, FDA Compliance/Regulatory Affairs, Medical, Briefs, MDB

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Portable Intravenous Fluid Production Device for Ground Use

This small, portable device with high output produces medical injection-grade sterile water from potable water sources. There are several medical conditions that require intravenous (IV) fluids. Limitations of mass, volume, storage space, shelf-life, transportation, and local resources can restrict the availability of such important fluids. These limitations are expected in long-duration space exploration missions and in remote or austere environments on Earth. Current IV fluid production requires large factory-based processes. Easy, portable, on site production of IV fluids can eliminate these limitations. Based on experience gained in developing a device for spaceflight, a grounduse device was developed.

Posted in: Bio-Medical, Medical, Drug Delivery & Fluid Handling, Briefs, MDB

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Development of a Low- Cost, Portable Biosensor for Blood Protein Detection

This innovation offers a high level of medical diagnostic sensing abilities comparable to more costly clinical instrumentation. Current blood testing procedures are expensive and time consuming, and the equipment required is often bulky and difficult to transport. A new low-cost, portable technique has been developed to quickly and reliably detect specific proteins in a sample of human blood. The technique, described in the Sept. 1, 2011 issue of the Optical Society’s (OSA) open-access journal, Biomedical Optics Express, could help in a wide range of medical sensing applications, including diagnosing diseases like cancer and diabetes long before clinical symptoms arise.

Posted in: Bio-Medical, Imaging & Diagnostics, Monitoring & Testing, Biosensors, Sensors, Medical, Diagnostics, Briefs, MDB

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Non-Invasive Instrument for Skin Cancer Screening

Andor Newton camera powers combined RS-OCT probe capable of both morphological and biochemical characterization of skin cancers. Skin cancer is the most common form of cancer in humans, with annual rates continuing to climb from their current estimate of just over three million new cases each year. Although all skin cancers share the likelihood of a favorable outcome if early diagnosis and complete resection are achieved, diagnosis is invasive, subjective, lengthy, and expensive, as it involves expert visual inspection, biopsy, and histopathology.

Posted in: Bio-Medical, Imaging & Diagnostics, Monitoring & Testing, Optics/Photonics, Cameras, Machine Vision, Visualization Software, Imaging, Medical, Diagnostics, Briefs, MDB

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