Medical

Experimental Modeling of Sterilization Effects for Atmospheric Entry Heating on Microorganisms

Silicon was chosen for sample coupons. The objective of this research was to design, build, and test an experimental apparatus for studying the parameters of atmospheric entry heating, and the inactivation of temperature-resistant bacterial spores. The apparatus is capable of controlled, rapid heating of sample coupons to temperatures of 200 to 350 ºC and above. The vacuum chamber permits operation under vacuum or special atmospheric gas mixtures.

Posted in: Bio-Medical, Medical, Briefs, TSP

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Saliva Preservative for Diagnostic Purposes

This preservative can be used in remote areas without refrigeration for at least two months. Saliva is an important body fluid for diagnostic purposes. Glycoproteins, glucose, steroids, DNA, and other molecules of diagnostic value are found in saliva. It is easier to collect as compared to blood or urine. Un for tunately, saliva also contains large numbers of bacteria that can release enzymes, which can degrade proteins and nucleic acids. These degradative enzymes destroy or reduce saliva’s diagnostic value. This innovation describes the formulation of a chemical preservative that prevents microbial growth and inactivates the degradative enzymes. This extends the time that saliva can be stored or transported without losing its diagnostic value. Multiple samples of saliva can be collected if needed without causing discomfort to the subject and it does not require any special facilities to handle after it is collected.

Posted in: Bio-Medical, Medical, Briefs, TSP

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Benefits of Using Rigorously Tested Routines From Numerical Libraries

This technology helps technical application developers incorporate mathematical and statistical functionality in their applications, while providing the documentation needed for software validation.

Posted in: Bio-Medical, Software, Mathematical/Scientific Software, Medical, Briefs, MDB

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Leak-Free Connection for Blood Pressure Monitoring Applications

Using proprietary molding techniques, the inner fitting features three sharp barbs designed specifically to securely hold the stiffer hoses common to blood pressure monitors. For precise blood pressure monitoring in hospitals and surgeries, the accurate handling of medical devices is paramount. Human error or device failure can result in inaccurate readings, which compromise the safety of patients, and it is critical, therefore, that device components, such as connectors, not only ensure a leak-free connection but are also simple and easy to use.

Posted in: Bio-Medical, Manufacturing & Prototyping, Medical, Patient Monitoring, Briefs, MDB

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Mini-Sensor Measures Magnetic Activity in Human Brain

A recent study indicates that the technology may be used in magnetoencephalography (MEG), a noninvasive procedure that could advance the study of neurological diseases. A miniature atom-based magnetic sensor has passed an important research milestone by successfully measuring human brain activity. Experiments verified the sensor's potential for biomedical applications such as studying mental processes and advancing the understanding of neurological diseases.

Posted in: Bio-Medical, Imaging, Sensors, Medical, Patient Monitoring, Briefs, MDB

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Hands-Free Transcranial Color Doppler Probe

These probes enable full use of TCD technology for neurological diagnostics. Current transcranial color Doppler (TCD) transducer probes are bulky and difficult to move in tiny increments to search and optimize TCD signals. This invention provides miniature motions of a TCD transducer probe to optimize TCD signals.

Posted in: Bio-Medical, Imaging, Medical, Patient Monitoring, Briefs, TSP, MDB

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Purifying, Separating, and Concentrating Cells From a Sample Low in Biomass

This fluorescence-activated cell-sorting-based approach has applications in operating room cleanliness validation assays, and in pharmaceutical development and quality assurance. Frequently there is an inability to process and analyze samples of low biomass due to limiting amounts of relevant biomaterial in the sample. Furthermore, molecular biological protocols geared towards increasing the density of recovered cells and biomolecules of interest, by their very nature, also concentrate unwanted inhibitory humic acids and other particulates that have an adversarial effect on downstream analysis.

Posted in: Bio-Medical, Medical, Briefs, TSP

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