Health, Medicine, & Biotechnology

Orthotic Dynamically Adjusts to Changes in Foot Structure and Movement

This orthotic insert mimics the experience of walking in wet sand.Kinesthotic© orthotics are made to adapt to the foot by replicating, within footwear, an explicit quality of beach-sand surface dynamics on whatever surface the footwear is used. The resulting support complies with the biomechanically sound and functional supportive principles and demands of each foot. The proprietary semi-fluid One-MinuteFit© molding composite is hermetically sealed within the Kinesthotic retaining envelope aligned on top of the pre-molded dynamic molding chassis.

Posted in: Briefs, MDB, Briefs, Medical, Rehabilitation & Physical Therapy


Reusable Personal Radiation Dosimeter for Ultraviolet or Radioactive Radiation

This inexpensive device is worn on clothing and is reusable.Radiation dosimeters are important for people working with radioactive isotopes, as in analytical research laboratories, in nuclear medical applications, in medical X-ray imaging, in nuclear power-stations, or in non-destructive testing of materials by ionizing radiation. They need to know their received radiation dose and need to be warned when threshold values are exceeded. Another area where personal radiation doses are important is in the exposure to ultraviolet (UV) light (UV-A , UV-B, and UV-C). Dose detection can be helpful for skin protection and damage prevention.

Posted in: Briefs, MDB, Briefs, Medical, Patient Monitoring


High-Altitude Hydration System

Multiple methods of keeping water from freezing can be used by law enforcement personnel, skiers, and campers, and underwater by military personnel.Three methods are being developed for keeping water from freezing during high-altitude climbs so that mountaineers can remain hydrated. Three strategies have been developed. At the time of this reporting two needed to be tested in the field and one was conceptual.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Medical


Eye, Ear, and Skin Scope

The handheld digital device has three attachable lenses for ear, eye, and skin imaging.A handheld, digitized ophthalmo scope, otoscope, or dermoscope takes digital images and video, and transmits the images to patients’ electronic medical records and/or to physicians for remote diagnosis. The device can be used for retinal (ophthalmoscopy), ear (otoscopy), or skin (dermatoscopy) imaging.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Diagnostics, Medical


Enhancing Tumor Drug Delivery by Laser-Activated Vascular Barrier Disruption

Photodynamic therapy is used to eradicate tumor tissue and provide enhanced drug delivery.An obstacle to successful cancer drug therapy is the existence of drug delivery barriers, which result in insufficient and heterogeneous drug delivery to the tumor tissue. This drug delivery problem not only limits the clinical application of existing chemotherapeutics, but also decreases the effectiveness of many new drugs under development. Photodynamic therapy (PDT), a modality involving the combination of a photo-sensitizer and laser light, is an established cancer therapy. This work demonstrates the effectiveness of vascular-targeting PDT in eradicating tumor tissue, and modifying vascular barrier function for enhanced drug delivery.

Posted in: Briefs, MDB, TSP, Briefs, TSP, Drug Delivery & Fluid Handling, Medical, Patient Monitoring, Lasers & Laser Systems, Photonics


Fast, Quantitative Diagnostic Reader for Multiple Medical Tests

Any test that attenuates light is a candidate for use with the device — potentially thousands of different tests.While most physicians have easy access to lab tests, those tests can be slow and expensive. Consumer versions of tests are inaccurate and have limited scope, and often involve sending a sample to a lab. Physicians, emergency rooms, EMTs, patients, visiting nurses, and caregivers may all need access to quick, accurate tests without waiting for results and making callbacks. Some chronic tests require the mixing of reagents, and so are difficult to perform at home.

Posted in: Briefs, MDB, Briefs, Diagnostics, Medical


Miniature Bioreactor System for Long-Term Cell Culture

Cells can be cultured and sampled with minimal human intervention.A prototype miniature bioreactor system is designed to serve as a laboratory benchtop cell-culturing system that minimizes the need for relatively expensive equipment and reagents and can be operated under computer control, thereby reducing the time and effort required of human investigators and reducing uncertainty in results. The system includes a bioreactor, a fluid-handling subsystem, a chamber wherein the bioreactor is maintained in a controlled atmosphere at a controlled temperature, and associated control subsystems. The system can be used to culture both anchorage-dependent and suspension cells, which can be either prokaryotic or eukaryotic. Cells can be cultured for extended periods of time in this system, and samples of cells can be extracted and analyzed at specified intervals. By integrating this system with one or more microanalytical instrument(s), one can construct a complete automated analytical system that can be tailored to perform one or more of a large variety of assays.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Diagnostics, Medical


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