Medical

Quantifying Therapeutic and Diagnostic Efficacy in 2D Microvascular Images

VESGEN is a newly automated, user- interactive program that maps and quantifies the effects of vascular therapeutics and regulators on microvascular form and function. VESGEN analyzes two- dimensional, black and white vascular images by measuring important vessel morphology parameters. This software guides the user through each required step of the analysis process via a concise graphical user interface (GUI). There are control options ranging from “one-click” analysis given a primary output, to step-by-step control over each image and algorithm used in an analysis. An option is provided to select a vascular tissue type, which determines the general collections of algorithms, intermediate images, and output images and measurements that will be produced. The UI automatically restructures itself to provide customized user controls for studying the requested type of tissue.

Posted in: Bio-Medical, Software, Medical, Diagnostics, Briefs, TSP, MDB

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Micro-Organ Devices

Effects of drugs can be tested realistically, without experimentation on animals. Micro-organ devices (MODs) are being developed to satisfy an emerging need for small, lightweight, reproducible, biological-experimentation apparatuses that are amenable to automated operation and that impose minimal demands for resources (principally, power and fluids). MODs are intended to overcome major disadvantages of conventional in vitro and conventional in vivo experimentation for purposes of investigating effects of medicines, toxins, and possibly other foreign substances.

Posted in: Bio-Medical, Medical, Drug Delivery & Fluid Handling, Patient Monitoring, Briefs, MDB

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Mulifunctional Electrosurgical Instrument

Several surgical tasks can be accomplished with a single, handheld instrument. The Multifunctional Electrosurgic Instrument (LESDIC) is an electrocauterizing surgical device that is comprised of a serrated chisel tip for sharp, blunt, or cutting dissection. It is also equipped with suctioning, irrigation, and coagulation features. The suction can be controlled at variable speeds and pressures. This electrosurgical instrument can be utilized in various surgical procedures such as mastectomies, tonsillectomies, repair of umbilical hernias, cosmetic surgeries, and ovarian surgeries, and operations involving all of the following procedures: cutting/dissecting, coagulating bleeding blood vessels, suctioning blood and smoke, and irrigating the surgical site as necessary.

Posted in: Bio-Medical, Treatment Devices, Medical, Briefs, MDB

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Sensory Feedback System for Prosthetic Hand Using Interferential Current

This sensory feedback system would help amputees execute fine tasks or handle delicate objects easily. A new type of sensory feedback system for a myoelectrically controlled biomimetic prosthetic hand was developed. One of the characteristic features of the human neuromuscular control system is the increase in the compliance around a joint with decreasing activity of a muscle. Interferential current that uses two waves and interferences was used to synthesize a low frequency in the body. One frequency was fixed at 4,000 Hz and the other frequency was changed from 3,700 Hz to 4,000 Hz. As a result, stimulus frequency in the body was changed from 0 Hz to 300 Hz. It was measured that the subjects could distinguish the change of stimulus frequency, and confirmed that the interference current is a useful method for sensibility feedback of a prosthetic hand.

Posted in: Bio-Medical, Sensors, Implants & Prosthetics, Medical, Briefs, TSP, MDB

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Remote Diagnostic Technology for Hearing Assessment

Clinicians can remotely assess, diagnose, and remedy hearing loss. Individuals with hearing loss need to have ready access to hearing screenings, assessments, treatment, and consultation. This diagnostic technology facilitates early detection and intervention of hearing loss. It allows for improved monitoring and expands service scope, reach, and access. By reducing or eliminating travel times, it is also a more efficient utilization of time for audiologists and professional staff. The tele-hearing device and protocol provides clinicians the tools and the ability to remotely assess, diagnose, and remedy hearing loss. This is accomplished either directly or indirectly by facilitating assistance to other less experienced clinicians remotely.

Posted in: Bio-Medical, Electronics & Computers, Electronics, Medical, Patient Monitoring, Briefs, MDB

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Three-Dimensional Near-Infrared Imaging of Pathophysiological Changes Within the Breast

New reconstruction method improves the quantitative and qualitative accuracy of NIR images. This project aims to improve the estimation of functional properties of breast tissue in near infrared (NIR) imaging. This imaging technique (also known as diffuse optical tomography (DOT)) is noninvasive and non-ionizing, and can be routinely used to characterize the breast tissue. In this technique, fibers placed on the boundary of the breast deliver NIR light (600 nm to 950 nm) and collect the propagated diffused light (the patient fiber-optic setup is shown in the photo). The attenuation and scattering of light through breast tissue volume provide an estimation of functional properties using a model-based approach.

Posted in: Bio-Medical, Medical, Diagnostics, Briefs, TSP, MDB

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Software Corrects for Inhomogeneities in Digital Radiographic Images

The corrected digital image can be used to enable computer-assisted diagnosis. When radiographic images are recorded, they are subject to inhomogeneities due to the construction of the radiation source and to the properties of the detection medium (detector or screen). As a result, erroneous results may appear when the digital images are processed to enhance diagnostic relevance. Software described here allows for the correction of these inhomogeneities, before any further processing of the digital images is undertaken.

Posted in: Bio-Medical, Software, Medical, Diagnostics, Briefs, MDB

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