Health, Medicine, & Biotechnology

Monolithically Integrated, Mechanically Resilient Carbon-Based Probes for Scanning Probe Microscopy

These probes can be used in medical applications for bacteria or protein imaging.Scanning probe microscopy (SPM) is an important tool for performing measurements at the nanoscale in imaging bacteria or proteins in biology, as well as in the electronics industry. An essential element of SPM is a sharp, stable tip that possesses a small radius of curvature to enhance spatial resolution. Existing techniques for forming such tips are not ideal. High-aspect-ratio, monolithically integrated, as-grown carbon nanofibers (CNFs) have been formed that show promise for SPM applications by overcoming the limitations present in wet chemical and separate substrate etching processes.

Posted in: Briefs, MDB, Briefs, Imaging, Bio-Medical, Diagnostics, Medical

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Ultra-High-Molecular-Weight Polyethylene Technology for Minimally Invasive Devices

Ultra-thin film and fiber are suitable for implantable cardiovascular devices.Ultra-high-molecular-weight polyethylene (UHMWPE) has been used for decades as a biomaterial in joint replacements. Recently, this technology was refined to serve the needs of minimally invasive surgical applications, particularly cardiovascular implants. UHMWPE fiber can be shaped into a range of textile constructions, including braids and woven tubes, while the film can be used as a very thin barrier or cover. As such, the medical-grade UHMWPE film and fiber are suitable for enhancing the design of various implantable cardiovascular devices, including stent grafts and covered stents.

Posted in: Briefs, MDB, Briefs, Coatings & Adhesives, Materials, Bio-Medical, Implants & Prosthetics, Medical

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Circulatory Assist Pump for Implantable Artificial Heart Device

This ventricular-assist pump can be used before and after surgery.When a patient’s heart disease cannot be treated, heart transplantation is required, but only a few people can receive transplants. These rare opportunities for transplantation have created a demand for artificial hearts.

Posted in: Briefs, MDB, Briefs, Mechanical Components, Bio-Medical, Medical

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Ultrasonic Echo Probe With Measurement of Contact Pressure Distribution

This probe can measure tissue inside living bodies non-invasively using a thin-film piezoelectric pressure sensor.This ultrasonic echo apparatus can measure tissue inside living bodies, non-invasively. The developed probe has a film-like piezoelectric sensor installed on the contact surface of an ordinary medical ultrasonic probe, and it can measure the contact pressure distribution between the probe and living bodies. Since it can measure, with an ultrasonic echo image, the deformation of living bodies when a probe is pressed against them dynamically, it can calculate the distribution of mechanical impedance within living bodies by using information on contact pressure at the contact surface.

Posted in: Features, MDB, Briefs, Bio-Medical, Medical, Sensors

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Modifying Polyethylene Oxide for Melt-Processability

Water-soluble packaging, disposable articles, and transdermal patches are possible applications for products made using water-soluble PEO.Generally, high-molecular-weight polyethylene oxide (PEO) can present processing challenges due to its high melt viscosity and poor melt drawability; it can be difficult to form into fine-gauge film or small-diameter fibers. There is the alternative technology of solution casting, which has occasionally been utilized to cast thin films; however, solution casting may not always be practical for large-scale, economically viable film production.

Posted in: Briefs, MDB, Briefs, Coatings & Adhesives, Materials, Bio-Medical, Medical

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Topical Compositions and Glove for Protection and Shielding Against Radiation Exposure

These technologies have applications in military, nuclear energy, and emergency preparedness.Over the past several decades, there has been a proliferation of medical diagnostic and treatment devices that involve the use of X-rays, beta rays, gamma rays, and radioactive isotopes. In addition, there has been recent concern regarding possible radiation exposure from nuclear weapons and terrorist attacks on nuclear facilities. Thus, there is a need for devices that can protect areas of the body that may be exposed to damaging radiation without hindering the user’s dexterity or loss of touch sensation.

Posted in: Briefs, MDB, Briefs, Coatings & Adhesives, Materials, Bio-Medical, Medical, Patient Monitoring

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Digital Microfluidics Sample Analyzer

Combined innovations enable portable analyzers for medical diagnostics, bioterrorism pathogen detection, and food supply analysis.Three innovations address the needs of the medical world with regard to microfluidic manipulation and testing of physiological samples in ways that can benefit point-of-care needs for patients such as premature infants, for which drawing of blood for continuous tests can be life-threatening in their own right, and for expedited results. A chip with sample injection elements, reservoirs (and waste), droplet formation structures, fluidic pathways, mixing areas, and optical detection sites, was fabricated to test the various components of the microfluidic platform, both individually and in integrated fashion. The droplet control system permits a user to control droplet microactuator system functions, such as droplet operations and detector operations. Also, the programming system allows a user to develop software routines for controlling droplet microactuator system functions, such as droplet operations and detector operations.

Posted in: Briefs, MDB, Briefs, Coatings & Adhesives, Materials, Bio-Medical, Diagnostics, Medical, Patient Monitoring, Software

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