Health, Medicine, & Biotechnology

Epiretinal Prosthesis Surgically Implanted in the Eye

A miniature video camera housed in a pair of glasses captures a scene and relays the information to a receiver in the implant.

In a healthy eye, the photoreceptors (rods and cones) on the retina convert light into tiny electrochemical impulses that are sent through the optic nerve and into the brain, where they are decoded into images. If the photoreceptors no longer function correctly — due to conditions such as retinitis pigmentosa — the first step in this process is disrupted, and the visual system cannot transform light into images.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Diagnostics, Implants & Prosthetics, Medical, Imaging and visualization, Body regions, Nervous system, Prostheses and implants
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Biosensing Technology Offers Advanced Diagnostic Capabilities

An electronic biosensing platform, combining nanoelectronics and three-dimensional electronic system integration, could replace the conventional microplate.

Electronic biosensing technology could someday displace the multi-welled microplate, long a standard tool in biomedical research and diagnostic laboratories. Essentially arrays of tiny test tubes, microplates have been used for decades to simultaneously test multiple samples for their responses to chemicals, living organisms, or antibodies. Fluorescence or color changes in labels associated with compounds on the plates can signal the presence of particular proteins or gene sequences.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Medical, Patient Monitoring, Sensors, Sensors and actuators, Biological sciences, Diagnostics, Test equipment and instrumentation
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Die Extrusion Technology for Medical Tubing Applications

Patent-pending process would allow 1000-plus layers from a single extruder.

Although the concept of nanotechnology (controlling matter on an atomic scale) dates back to 1959, it is only now becoming more commercially realized. It has the potential to challenge the way all products are extruded in almost every type of medical tubular or related industrial product applications.

Posted in: Briefs, MDB, Briefs, Contract Services, Custom & Contract Manufacturing, Manufacturing & Prototyping, Materials, Bio-Medical, Medical, Nanotechnology, Medical equipment and supplies, Extrusion, Nanotechnology, Hoses, Industrial vehicles and equipment
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Blood Pressure Monitoring Tool

A computer control mouse device includes a sphygmomanometer and software package to take recordings and store them as digital data.

The MDMouse system incorporates a pre-existing medical device into a conventional computer control mouse. The tool is designed to measure blood pressure outside of the medical environment, and to provide that information for use by individuals, clinical evaluation companies (CROs), healthcare providers, and healthcare payers.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Medical, Patient Monitoring, Software, Computer software and hardware, Fluids and secretions, Medical equipment and supplies, Physical examination
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Laser Sintering for Customized Medical Applications

Additive, layer-by-layer manufacturing process allows for the manufacture of complex geometries in plastic and metal implants and orthoses.

Engineers have long been aware of the potential of laser sintering to create innovative and beneficial medical products. Because it is an additive (layer-by-layer) manufacturing process, laser sintering can build parts free of the traditional constraints imposed by machining or molding.

Recent medical applications of laser sintering are now demonstrating the technology’s unique capabilities for mass customization and the manufacture of designs with complex geometries in both plastics and metals.

Posted in: Briefs, MDB, Briefs, Contract Services, Custom & Contract Manufacturing, Manufacturing & Prototyping, Bio-Medical, Implants & Prosthetics, Medical, Lasers, Medical equipment and supplies, Heat treatment
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Cubic-Millimeter Energy-Autonomous Wireless Intraocular Pressure Monitor

Once implanted in the eye, this complete millimeter-scale computing system tracks the progress of glaucoma.

A prototype implantable eye pressure monitor for glaucoma patients is believed to contain the first complete millimeter-scale computing system. The pressure monitor is designed to be implanted in the eye to conveniently and continuously track the progress of glaucoma, a potentially blinding disease. It is expected to be commercially available in several years.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Implants & Prosthetics, Medical, Patient Monitoring, Embedded software, Sensors and actuators, Diseases, Prostheses and implants
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Single, Stationary Lens Able to Create Microscopic 3D Images

Freeform lens could someday provide a proof of concept for manufacturers of microelectronics and medical devices.

A lens that enables microscopic objects to be seen from nine different angles at once to create a 3D image has been developed. Other 3D microscopes use multiple lenses or cameras that move around an object; the new lens is the first single, stationary lens to create microscopic 3D images by itself.

Posted in: Briefs, MDB, Briefs, Manufacturing & Prototyping, Bio-Medical, Diagnostics, Medical, Photonics, CAD, CAM, and CAE, Microscopy, Product development, Thermoplastics
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Design Considerations for Battery Connectors

As medical devices become more portable and miniaturized, their power connections must evolve to meet these demands.

The future of batteries, like that of so many medical devices they power, is clearly toward smaller, lighter, and more powerful models. Developing concurrently with these new battery designs are battery connectors. As battery connection devices evolve, they have to meet a number of challenges, including: rapid growth of designs; rugged construction; high-density packaging; manufacturing costs; and environmental concerns.

Posted in: Briefs, MDB, Briefs, Electronics, Electronics & Computers, Bio-Medical, Medical, Design processes, Lithium-ion batteries, Medical equipment and supplies
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Method of Reducing Stray Energy Burns in Laparoscopic Surgery

Active Electrode Monitoring (AEM) instruments incorporate a “shielded and monitored” design to lower risk of injury.

Any surgery brings with it risk, both to the patient and the surgeon. However, laparoscopic surgery sometimes brings an additional invisible risk: stray energy burns. Electrosurgical devices and laparoscopic instruments can suffer insulation failures and capacitive coupling, potentially causing stray energy burns to the patient. Often these burns occur out of sight of the surgeon and may go unnoticed until the patient presents with symptoms like peritonitis or sepsis.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Medical, Lasers & Laser Systems, Photonics, Robotics, Lasers, Surgical procedures, Risk management, Injuries
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Ultra-Miniature Image Sensor

A wafer-level camera operates at low power and may be customized for application needs, which include endoscopy, surgical robots, and 3D model generation.

Minimally invasive surgery has increasingly required imaging devices to have the smallest possible dimensions but also deliver high-resolution vision capabilities. There has also been a rising demand for disposable medical devices. With these criteria in mind, in 2004, the first prototype of the NanEye sensor was created in the lab. The miniature 0.25 mm2 camera module measured 0.5 mm × 0.5 mm, with 140 × 140 pixels at a frame rate of 40 frames/second.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Diagnostics, Medical, Sensors, Imaging and visualization, Sensors and actuators, Medical equipment and supplies, Surgical procedures
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