Health, Medicine, & Biotechnology

Engineering Devices to Treat Epilepsy

Intelligent implantable epilepsy devices will likely be tuned to individual patients, and may need to predict events rather than merely detect them. Many technologies have been proposed for treating epileptic seizures, with the ultimate goal being implantation of stimulators or drug infusion devices in the brain to abort seizures before clinical onset. Device designs range from “blind” stimulators to “intelligent” devices, which are triggered by detecting or predicting seizure onset. Intelligent implantable epilepsy devices will likely process multiple channels of data, be tuned to individual patients, and may need to predict events rather than merely detect them.

Posted in: Treatment Devices, Bio-Medical, Briefs, TSP, Briefs, TSP, Drug Delivery & Fluid Handling, Implants & Prosthetics

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More-Realistic Digital Modeling of a Human Body

A MATLAB computer program has been written to enable improved (relative to an older program) modeling of a human body for purposes of designing space suits and other hardware with which an astronaut must interact. The older program implements a kinematic model based on traditional anthropometric measurements that do provide important volume and surface information. The present program generates a three-dimensional (3D) whole-body model from 3D body-scan data. The program utilizes thin-plate spline theory to reposition the model without need for additional scans.

Posted in: Bio-Medical, Briefs, Briefs

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Optoelectronic pH Meter: Further Details

A collection of documents provides further detailed information about an optoelectronic instrument that measures the pH of an aqueous cell-culture medium to within ±0.1 unit in the range from 6.5 to 7.5. The instrument at an earlier stage of development was reported in “Optoelectronic Instrument Monitors pH in a Culture Medium” (MSC-23107), NASA Tech Briefs, Vol. 28, No. 9 (September 2004), page 4a.

Posted in: Bio-Medical, Briefs, TSP

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Magnetic Plungerless Injection System

This system provides an enclosed and completely sealed system that preserves sterility, and both injects and extracts liquid or gas substances. The Magnetic Plungerless Injection System (MPIS) was invented to enhance the therapeutic value and market availability of parenterally delivered pharmaceuticals and vaccines. The MPIS is a mechanical arrangement of a proprietary single-dosage cartridge and a magnetic actuator, and is a combination of the storage and the injector/extractor (syringe). The design answers many questions raised by the existing hypodermic syringe.

Posted in: Bio-Medical, Briefs, Briefs, Drug Delivery & Fluid Handling

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Exact Dose Dispensing Closure for Semi-Solids

This device replaces a conventional tube cap and enables a user to dispense an exact dose. A novel closure technology now makes it possible to consistently squeeze an exact dose of semi-solids from a tube by means of a 180-degree rotating closure. It has potential uses in pharmaceutical transdermal and oral applications, as well as glue dispensing, semi-solid food dispensing, and paint dispensing. Other potential applications are exact dose dispensing of prescription toothpaste, food condiments, or cosmetic products such as sunscreen creams and skin care formulations.

Posted in: Bio-Medical, Briefs, Briefs, Drug Delivery & Fluid Handling

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Graphite Non-Wovens as Functional Layers in Diagnostic Test Kits

Blood-handling diagnostic test strips can be used for diabetes testing and monitoring, and testing for other diseases. The separation of serum or plasma from whole blood is of overriding importance in clinical chemistry. In particular, many diagnostic detection reactions of blood components proceed without impairment only after the red blood corpuscles have been separated off. This particularly applies to color reactions that are evaluated either by reflectometry or visually, or also electrochemically.

Posted in: Briefs, Briefs, Coatings & Adhesives, Patient Monitoring

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Modular Electronic Air Sterilization Technology

This germicidal irradiation system eliminates airborne bacteria, molds, and viruses in one pass. Ultraviolet germicidal irradiation (UVGI) technologies are being used as infection control devices, primarily in healthcare facilities. No standard exists, but the dose of UV and the airflow are critical to ensuring all contaminated air is treated. The UVGI process is mainly influenced by the microorganism population, the irradiation intensity, and the intimate exposure time to the lamps. This new technology enables the system to increase the intensity field or to improve the inactivation process, without adding more energy or increasing the output efficiency of the lamps.

Posted in: Bio-Medical, Briefs, Briefs, Electronics

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