Health, Medicine, & Biotechnology

More-Realistic Digital Modeling of a Human Body

A MATLAB computer program has been written to enable improved (relative to an older program) modeling of a human body for purposes of designing space suits and other hardware with which an astronaut must interact. The older program implements a kinematic model based on traditional anthropometric measurements that do provide important volume and surface information. The present program generates a three-dimensional (3D) whole-body model from 3D body-scan data. The program utilizes thin-plate spline theory to reposition the model without need for additional scans.

Posted in: Briefs, MDB, Briefs, Medical, Software


Optoelectronic pH Meter: Further Details

A collection of documents provides further detailed information about an optoelectronic instrument that measures the pH of an aqueous cell-culture medium to within ±0.1 unit in the range from 6.5 to 7.5. The instrument at an earlier stage of development was reported in “Optoelectronic Instrument Monitors pH in a Culture Medium” (MSC-23107), NASA Tech Briefs, Vol. 28, No. 9 (September 2004), page 4a.

Posted in: Briefs, TSP, Medical


Magnetic Plungerless Injection System

This system provides an enclosed and completely sealed system that preserves sterility, and both injects and extracts liquid or gas substances. The Magnetic Plungerless Injection System (MPIS) was invented to enhance the therapeutic value and market availability of parenterally delivered pharmaceuticals and vaccines. The MPIS is a mechanical arrangement of a proprietary single-dosage cartridge and a magnetic actuator, and is a combination of the storage and the injector/extractor (syringe). The design answers many questions raised by the existing hypodermic syringe.

Posted in: Briefs, MDB, Briefs, Drug Delivery & Fluid Handling, Medical


Exact Dose Dispensing Closure for Semi-Solids

This device replaces a conventional tube cap and enables a user to dispense an exact dose. A novel closure technology now makes it possible to consistently squeeze an exact dose of semi-solids from a tube by means of a 180-degree rotating closure. It has potential uses in pharmaceutical transdermal and oral applications, as well as glue dispensing, semi-solid food dispensing, and paint dispensing. Other potential applications are exact dose dispensing of prescription toothpaste, food condiments, or cosmetic products such as sunscreen creams and skin care formulations.

Posted in: Briefs, MDB, Briefs, Drug Delivery & Fluid Handling, Medical


Graphite Non-Wovens as Functional Layers in Diagnostic Test Kits

Blood-handling diagnostic test strips can be used for diabetes testing and monitoring, and testing for other diseases. The separation of serum or plasma from whole blood is of overriding importance in clinical chemistry. In particular, many diagnostic detection reactions of blood components proceed without impairment only after the red blood corpuscles have been separated off. This particularly applies to color reactions that are evaluated either by reflectometry or visually, or also electrochemically.

Posted in: Briefs, MDB, Briefs, Coatings & Adhesives, Materials, Medical, Patient Monitoring


Modular Electronic Air Sterilization Technology

This germicidal irradiation system eliminates airborne bacteria, molds, and viruses in one pass. Ultraviolet germicidal irradiation (UVGI) technologies are being used as infection control devices, primarily in healthcare facilities. No standard exists, but the dose of UV and the airflow are critical to ensuring all contaminated air is treated. The UVGI process is mainly influenced by the microorganism population, the irradiation intensity, and the intimate exposure time to the lamps. This new technology enables the system to increase the intensity field or to improve the inactivation process, without adding more energy or increasing the output efficiency of the lamps.

Posted in: Briefs, MDB, Briefs, Electronics, Electronics & Computers, Medical


Quantifying Therapeutic and Diagnostic Efficacy in 2D Microvascular Images

VESGEN is a newly automated, userinteractive program that maps and quantifies the effects of vascular therapeutics and regulators on microvascular form and function. VESGEN analyzes two-dimensional, black and white vascular images by measuring important vessel morphology parameters. This software guides the user through each required step of the analysis process via a concise graphical user interface (GUI). There are control options ranging from “one-click” analysis given a primary output, to step-by-step control over each image and algorithm used in an analysis. An option is provided to select a vascular tissue type, which determines the general collections of algorithms, intermediate images, and output images and measurements that will be produced. The UI automatically restructures itself to provide customized user controls for studying the requested type of tissue.

Posted in: Briefs, MDB, Briefs, Diagnostics, Medical, Software


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