Medical

Multiaxis, Lightweight, Computer-Controlled Exercise System

This system offers unprecedented versatility for physical conditioning and evaluation The multipurpose, multiaxial, isokinetic dynamometer (MMID) is a computer-controlled system of exercise machinery that can serve as a means for quantitatively assessing a subject’s muscle coordination, range of motion, strength, and overall physical condition with respect to a wide variety of forces, motions, and exercise regimens. The MMID is easily reconfigurable and compactly stowable and, in comparison with prior computer-controlled exercise systems, it weighs less, costs less, and offers more capabilities.

Posted in: Medical, Briefs

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Production of Tuber-Inducing Factor

This substance regulates the growth of potatoes and some other plants. A process for making a substance that regulates the growth of potatoes and some other economically important plants has been developed. The process also yields an economically important by-product: potatoes.

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Vacuum-Assisted, Constant- Force Exercise Device

An important advantage over other exercise machines would be light weight.

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Studying Functions of All Yeast Genes Simultaneously

This method could accelerate research on treatment of some diseases.

Posted in: Medical, Briefs

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Microfluidic Devices for Studying Biomolecular Interactions

These devices can be fabricated rapidly and inexpensively. Microfluidic devices for monitoring biomolecular interactions have been invented. These devices are basically highly miniaturized liquid-chromatography columns. They are intended to be prototypes of miniature analytical devices of the “laboratory on a chip” type that could be fabricated rapidly and inexpensively and that, because of their small sizes, would yield analytical results from very small amounts of expensive analytes (typically, proteins). Other advantages to be gained by this scaling down of liquid-chromatography columns may include increases in resolution and speed, decreases in the consumption of reagents, and the possibility of performing multiple simultaneous and highly integrated analyses by use of multiple devices of this type, each possibly containing multiple parallel analytical microchannels.

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Neuro-Prosthetic Implants With Adjustable Electrode Arrays

Depths of penetration of electrodes would be adjusted to maximize received signals. Brushlike arrays of electrodes packaged with application-specific integrated circuits (ASICs) are undergoing development for use as electronic implants — especially as neuro-prosthetic devices that might be implanted in brains to detect weak electrical signals generated by neurons. These implants partly resemble the ones reported in “Integrated Electrode Arrays for Neuro-Prosthetic Implants” (NPO-21198), NASA Tech Briefs, Vol. 27, No. 2 (February 2003), page 48. The basic idea underlying both the present and previously reported implants is that the electrodes would pick up signals from neurons and the ASICs would amplify and otherwise preprocess the signals for monitoring by external equipment.

Posted in: Bio-Medical, Medical, Briefs

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Biomimetic/Optical Sensors for Detecting Bacterial Species

Bacteria in liquid samples could be detected in real time. Biomimetic/optical sensors have been proposed as means of real-time detection of bacteria in liquid samples through real-time detection of compounds secreted by the bacteria. Bacterial species of interest would be identified through detection of signaling compounds unique to those species. The best-characterized examples of quorum- signaling compounds are acylhomoserine lactones and peptides. Each compound, secreted by each bacterium of an affected species, serves as a signal to other bacteria of the same species to engage in a collective behavior when the population density of that species reaches a threshold level analogous to a quorum.

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