Health, Medicine, & Biotechnology

Remote Diagnostic Technology for Hearing Assessment

Clinicians can remotely assess, diagnose, and remedy hearing loss.

Individuals with hearing loss need to have ready access to hearing screenings, assessments, treatment, and consultation. This diagnostic technology facilitates early detection and intervention of hearing loss. It allows for improved monitoring and expands service scope, reach, and access. By reducing or eliminating travel times, it is also a more efficient utilization of time for audiologists and professional staff. The tele-hearing device and protocol provides clinicians the tools and the ability to remotely assess, diagnose, and remedy hearing loss. This is accomplished either directly or indirectly by facilitating assistance to other less experienced clinicians remotely.

Posted in: Briefs, MDB, Briefs, Electronics, Electronics & Computers, Bio-Medical, Medical, Patient Monitoring, Internet, Internet, Diagnosis, Medical equipment and supplies, Nervous system, Noise, Noise
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Three-Dimensional Near-Infrared Imaging of Pathophysiological Changes Within the Breast

New reconstruction method improves the quantitative and qualitative accuracy of NIR images.

This project aims to improve the estimation of functional properties of breast tissue in near infrared (NIR) imaging. This imaging technique (also known as diffuse optical tomography (DOT)) is noninvasive and non-ionizing, and can be routinely used to characterize the breast tissue. In this technique, fibers placed on the boundary of the breast deliver NIR light (600 nm to 950 nm) and collect the propagated diffused light (the patient fiber-optic setup is shown in the photo). The attenuation and scattering of light through breast tissue volume provide an estimation of functional properties using a model-based approach.

Posted in: Briefs, MDB, TSP, Briefs, TSP, Bio-Medical, Diagnostics, Medical, Fiber optics, Imaging, Imaging and visualization, Fiber optics, Imaging, Imaging and visualization, Body regions, Diseases, Medical equipment and supplies
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Software Corrects for Inhomogeneities in Digital Radiographic Images

The corrected digital image can be used to enable computer-assisted diagnosis.

When radiographic images are recorded, they are subject to inhomogeneities due to the construction of the radiation source and to the properties of the detection medium (detector or screen). As a result, erroneous results may appear when the digital images are processed to enhance diagnostic relevance. Software described here allows for the correction of these inhomogeneities, before any further processing of the digital images is undertaken.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Diagnostics, Medical, Software, Mathematical models, Computer software / hardware, Computer software and hardware, Imaging, Imaging and visualization, Computer software / hardware, Computer software and hardware, Imaging, Imaging and visualization, Diagnosis, Radiation
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Nano-Pervaporation Membrane With Heat Exchanger Generates Medical-Grade Water

A small system produces high-quality water using a heat exchanger that meets requirements for evaporation of substances such as pharmaceuticals and vitamins.

A nanoporous membrane is used for the pervaporation process in which potable water is maintained, at atmospheric pressure, on the feed side of the membrane. The water enters the non- pervaporation (NPV) membrane device where it is separated into two streams — retentate water and permeated water. The permeated pure water is removed by applying low vapor pressure on the permeate side to create water vapor before condensation. This permeated water vapor is subsequently condensed by coming in contact with the cool surface of a heat exchanger with heat being recovered through transfer to the feed water stream.

Posted in: Briefs, MDB, Briefs, Electronics, Electronics & Computers, Bio-Medical, Medical, Water, Heat exchangers, Heat exchangers, Nanomaterials
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Wireless Brain Implant Using a Telemetric Electrode Array System

A 3D intra-cortical electrode array is embedded for signal acquisition, processing, and wireless communication.

The ability to monitor the activities of ensembles of single neurons is critically important in understanding the principles of information processing in the brain that underlie perception, cognition, and action. Multiple microelectrode recording using appropriate neuronal implants provides this ability. The Telemetric Electrode Array System (TEAS) project aims at developing and embedding a three-dimensional intra-cortical electrode array with all electronics required for signal acquisition, processing, and wireless communication entirely into the head.

Posted in: Briefs, MDB, TSP, Briefs, TSP, Electronics, Electronics & Computers, Bio-Medical, Implants & Prosthetics, Medical, Wireless communication systems, Wireless communication systems, Nervous system, Prostheses and implants
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Digital Wound Measurement and Tracking System

This Web-based platform tracks, documents, and measures the efficacy of wound treatments.

Historically, the subjective nature of wound treatment has lead to many trial-and-error therapies to match wounds with the right treatment. The WoundMatrix™ digital wound measurement and tracking system provides an objective and qualitative tool and method to track, document, and measure the efficacy of wound treatments.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Medical, Software, Computer software / hardware, Computer software and hardware, Imaging, Imaging and visualization, Computer software / hardware, Computer software and hardware, Imaging, Imaging and visualization, Medical equipment and supplies, Physical examination
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Biomedical Wireless Ambulatory Crew Monitor

A compact, ambulatory biometric data acquisition system has been developed for space and commercial terrestrial use. BioWATCH (Bio medical Wireless and Ambulatory Telemetry for Crew Health) acquires signals from bio-medical sensors using acquisition modules attached to a common data and power bus. Several slots allow the user to configure the unit by inserting sensor-specific modules. The data are then sent real-time from the unit over any commercially implemented wireless network including 802.11b/g, WCDMA, 3G.

Posted in: Briefs, TSP, Bio-Medical, Medical, Data acquisition and handling, Sensors and actuators, Wireless communication systems, Data acquisition and handling, Sensors and actuators, Wireless communication systems, Medical equipment and supplies
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Three-Dimensional Optical Coherence Tomography

Advantages over prior OCT systems include less bulk and greater speed.

Three-dimensional (3D) optical coherence tomography (OCT) is an advanced method of noninvasive infrared imaging of tissues in depth. Heretofore, commercial OCT systems for 3D imaging have been designed principally for external ophthalmological examination. As explained below, such systems have been based on a one- dimensional OCT principle, and in the operation of such a system, 3D imaging is accomplished partly by means of a combination of electronic scanning along the optical (Z) axis and mechanical scanning along the two axes (X and Y) orthogonal to the optical axis.

Posted in: Briefs, MDB, TSP, Briefs, TSP, Bio-Medical, Diagnostics, Medical, Imaging, Imaging and visualization, Imaging, Imaging and visualization, Biological sciences, Medical equipment and supplies, Technical reference, Technical review
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Isolation of Precursor Cells From Waste Solid Fat Tissue

A process for isolating tissue-specific progenitor cells exploits solid fat tissue obtained as waste from such elective surgical procedures as abdominoplasties (“tummy tucks”) and breast reductions. Until now, a painful and risky process of aspiration of bone marrow has been used to obtain a limited number of tissue-specific progenitor cells.

Posted in: Briefs, MDB, TSP, Briefs, TSP, Bio-Medical, Medical, Patient Monitoring, Fluids and secretions, Surgical procedures
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Benchtop Antigen Detection Technique Using Nanofiltration and Fluorescent Dyes

This technique can help to monitor the quality of water by testing for contamination at restaurants, water treatment plants, and food processing plants.

The designed benchtop technique is primed to detect bacteria and viruses from antigenic surface marker proteins in solutions, initially water. This inclusive bio-immunoassay uniquely combines nanofiltration and near infrared (NIR) dyes conjugated to antibodies to isolate and distinguish microbial antigens, using laser excitation and spectrometric analysis. The project goals include detecting microorganisms aboard the International Space Station, space shuttle, Crew Exploration Vehicle (CEV), and human habitats on future Moon and Mars missions, ensuring astronaut safety. The technique is intended to improve and advance water contamination testing both commercially and environmentally as well. Lastly, this streamlined technique poses to greatly simplify and expedite testing of pathogens in complex matrices, such as blood, in hospital and laboratory clinics.

Posted in: Briefs, MDB, TSP, Briefs, TSP, Bio-Medical, Medical, Patient Monitoring, Water pollution, Bacteria, Test procedures, Spacecraft
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