Health, Medicine, & Biotechnology

Hydrofocusing Bioreactor Produces Anti-Cancer Alkaloids

Enhancement of production may be attributable to favorable aggregation of cells.

A methodology for growing three-dimensional plant tissue models in a hydrodynamic focusing bioreactor (HFB) has been developed. The methodology is expected to be widely applicable, both on Earth and in outer space, as a means of growing plant cells and aggregates thereof under controlled conditions for diverse purposes, including research on effects of gravitation and other environmental factors upon plant growth and utilization of plant tissue cultures to produce drugs in quantities greater and at costs lower than those of conventional methodologies

Posted in: Briefs, TSP, Bio-Medical, Medical, Biological sciences
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A Miniaturized Video System for Monitoring Drosophila Behavior

This method allows monitoring the movement of many fruit flies in space simultaneously.

Long-term spaceflight may induce a variety of harmful effects in astronauts, resulting in altered motor and cognitive behavior. The stresses experienced by humans in space — most significantly weightlessness (microgravity) and cosmic radiation — are difficult to accurately simulate on Earth. In fact, prolonged and concomitant exposure to microgravity and cosmic radiation can only be studied in space.

Posted in: Briefs, TSP, Bio-Medical, Medical, Human factors, Mental processes, Radiation
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Biomedical Textile Material Selection and Performance Considerations in Device Design

Biocompatible materials are increasingly being refined for incorporation in therapeutic applications.

Biomedical textile structures incorporate a wide array of biocompatible materials, including advanced polymers and metals in a range of sizes and thicknesses with varying material characteristics and performance properties. Promising substrates, now in development, add to the diversity of biomedical textile structure options. This versatility puts device designers within reach of developing highly complex, ultra-sophisticated components that can be used in a number of therapeutic applications, including orthopedics, cardiovascular, tissue engineering, neurology, and general surgery.

Posted in: Briefs, MDB, Briefs, Coatings & Adhesives, Materials, Bio-Medical, Implants & Prosthetics, Medical, Medical equipment and supplies, Biomaterials, Materials identification, Metals, Polymers, Textiles
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SCAFTEX® Non-Woven Bio-Textile for Implantable Devices

With the ability to encourage cellular in-growth, this material may become increasingly important to orthopedic reconstruction.

Classic tissue engineering utilizes absorbable non-woven biomedical textiles from a variety of fibers to aid in cell growth and proliferation, and medical device companies rely on these materials for implantable devices that must degrade over time. Non-woven bio-textiles such as SCAFTEX® and others have become the material of choice for many tissue engineering and regenerative medicine applications, and with superior surface area, high void volume, and excellent permeability, they are now also increasingly used in a wide variety of restorative applications ranging from orthopedic reconstruction and wound management to cosmetic surgery.

Posted in: Briefs, MDB, Briefs, Coatings & Adhesives, Materials, Bio-Medical, Implants & Prosthetics, Medical, Prostheses and implants, Suppliers, Biomaterials, Textiles
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Stereotactic System for Localizing Intracranial Targets

This technology helps guide instruments including biopsy forceps, deep brain electrodes, and endoscopes.

The CRW® stereotactic system, first released in 1988, was recently updated to focus on decreasing the steps to assemble the system while maintaining ±0.5 mm accuracy. This multi-purpose system is useful for localizing intracranial targets for precisely directing instruments. It is indicated for use in neurological procedures that require precise target localization such as craniotomies, biopsies, and functional neurosurgery. Typical instruments guided by CRW systems include biopsy forceps, radiofrequency lesioning electrodes, deep brain electrodes, recording and stimulating electrodes, hematoma evacuators, and endoscopes.

Posted in: Briefs, MDB, Briefs, Mechanical Components, Bio-Medical, Diagnostics, Medical, Electronic control systems, Electronic control systems, Medical equipment and supplies, Nervous system, Surgical procedures
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Microwave Tissue Soldering for Immediate Wound Closure

Wounds can be closed rapidly, without staples, sutures, or tapes.

A novel approach for the immediate sealing of traumatic wounds is under development. A portable microwave generator and handheld antenna are used to seal wounds, binding the edges of the wound together using a biodegradable protein sealant or “solder.” This method could be used for repairing wounds in emergency settings, by restoring the wound surface to its original strength within minutes. This technique could also be utilized for surgical purposes involving solid visceral organs (i.e., liver, spleen, and kidney) that currently do not respond well to ordinary surgical procedures.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Medical, Lasers & Laser Systems, Photonics, Antennas, Antennas, Medical equipment and supplies, Adhesives and sealants, Injuries
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CyberKnife® Robotic Radiosurgery System Offers Precise, Customizable Care

Advanced visualization capabilities and segmentation capabilities help spare healthy tissue and minimize complications.

In the field of radiation oncology, the CyberKnife® Robotic Radiosurgery System is capable of delivering high doses of radiation with submillimeter accuracy anywhere in the body. The newest addition to the CyberKnife® product line, the CyberKnife® VSITM System, leverages and extends the benefits of radiosurgery — high accuracy and excellent healthy tissue sparing — to enable delivery of high-precision radiation therapy. VSI (which stands for Versatile, Simple, and Intelligent) gives clinicians greater versatility by providing additional options for them to consider when determining the optimal course of treatment for each patient, whether it is hypo-fractionated radiosurgery or conventionally fractionated robotic intensity-modulated radiation therapy (IMRT™). This enables physicians to customize care around the unique needs of each patient, thereby expanding the population of patients who can benefit from this system’s precision.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Diagnostics, Medical, Diseases, Medical equipment and supplies, Surgical procedures, Robotics, Radiation
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3D Constrained Surface Controller for Medical Imaging

A novel human interface device allows radiologists to concentrate on the diagnostic image rather than operating the interface.

To make diagnoses from imaging technologies such as computerized tomography (CT) and magnetic resonance imaging (MRI), radiologists use 2D image planes that slice through these data at a variety of angles to obtain the most clinically informative view. However, current approaches used to orient the 2D image plane within the 3D data are cumbersome and visually distracting. Typically, current commercial medical workstations require several mouse interactions with multiple reference images to select, drag, and rotate reference lines or buttons as part of this process.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Diagnostics, Medical, Magnetic resonance imaging (MRI), Magnetic resonance imaging (MRI), Human machine interface (HMI), Medical equipment and supplies
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Positioning Technology for Digital Displays on Mobile Medical Equipment

Mounting arm is useful for mobile ultrasound and X-ray applications.

As hospitals and surgical centers add more portable medical equipment, the precision and positioning of digital displays become critical to staff efficiency, comfort, and health. Dispensing quality healthcare depends on providers having easy access to the right tools and supplies. Clinicians and technicians need information at their fingertips to perform their jobs in situations where every second counts. Point-of-care portable medical equipment — for diagnostics, monitoring, and treatment — has helped speed up patient service, but it frequently comes with tradeoffs for healthcare workers. Mobile-mounted video displays and computer screens are not always well suited for sharing among workers of different body proportions, causing user frustration and, frequently, physical pain. This includes repetitive motion ailments, sore necks and backs, and eyestrain from less-than-optimal viewing angles.

Posted in: Briefs, MDB, Briefs, Mechanical Components, Bio-Medical, Diagnostics, Medical, Medical equipment and supplies, Displays, Displays, Customization
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Implantable Contact System for Medical Pulse Generation Devices

Stack integrates electrical contacts and isolation seals to serve as a scalable solution for lead interfaces in implantable devices used in cardiac rhythm management and neuromodulation.

An integrated seal and electrical contact system for medical implantable pulse generators (IPGs) has been engineered to help large and small OEMs accelerate the development process, reduce device volume, and improve functionality.

Posted in: Briefs, MDB, Briefs, Electronics, Electronics & Computers, Bio-Medical, Implants & Prosthetics, Medical, Connectors and terminals, Connectors and terminals, Prostheses and implants, Seals and gaskets
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