Health, Medicine, & Biotechnology

Laser Sintering for Customized Medical Applications

Additive, layer-by-layer manufacturing process allows for the manufacture of complex geometries in plastic and metal implants and orthoses.

Engineers have long been aware of the potential of laser sintering to create innovative and beneficial medical products. Because it is an additive (layer-by-layer) manufacturing process, laser sintering can build parts free of the traditional constraints imposed by machining or molding.

Recent medical applications of laser sintering are now demonstrating the technology’s unique capabilities for mass customization and the manufacture of designs with complex geometries in both plastics and metals.

Posted in: Briefs, MDB, Briefs, Contract Services, Custom & Contract Manufacturing, Manufacturing & Prototyping, Bio-Medical, Implants & Prosthetics, Medical, Lasers, Lasers, Medical equipment and supplies, Heat treatment
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Cubic-Millimeter Energy-Autonomous Wireless Intraocular Pressure Monitor

Once implanted in the eye, this complete millimeter-scale computing system tracks the progress of glaucoma.

A prototype implantable eye pressure monitor for glaucoma patients is believed to contain the first complete millimeter-scale computing system. The pressure monitor is designed to be implanted in the eye to conveniently and continuously track the progress of glaucoma, a potentially blinding disease. It is expected to be commercially available in several years.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Implants & Prosthetics, Medical, Patient Monitoring, Embedded software, Sensors and actuators, Embedded software, Sensors and actuators, Diseases, Prostheses and implants
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Single, Stationary Lens Able to Create Microscopic 3D Images

Freeform lens could someday provide a proof of concept for manufacturers of microelectronics and medical devices.

A lens that enables microscopic objects to be seen from nine different angles at once to create a 3D image has been developed. Other 3D microscopes use multiple lenses or cameras that move around an object; the new lens is the first single, stationary lens to create microscopic 3D images by itself.

Posted in: Briefs, MDB, Briefs, Manufacturing & Prototyping, Bio-Medical, Diagnostics, Medical, Photonics, CAD / CAM / CAE, CAD, CAM, and CAE, Microscopy, Microscopy, Product development, Thermoplastics
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Design Considerations for Battery Connectors

As medical devices become more portable and miniaturized, their power connections must evolve to meet these demands.

The future of batteries, like that of so many medical devices they power, is clearly toward smaller, lighter, and more powerful models. Developing concurrently with these new battery designs are battery connectors. As battery connection devices evolve, they have to meet a number of challenges, including: rapid growth of designs; rugged construction; high-density packaging; manufacturing costs; and environmental concerns.

Posted in: Briefs, MDB, Briefs, Electronics, Electronics & Computers, Bio-Medical, Medical, Design processes, Lithium-ion batteries, Lithium-ion batteries, Medical equipment and supplies
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Method of Reducing Stray Energy Burns in Laparoscopic Surgery

Active Electrode Monitoring (AEM) instruments incorporate a “shielded and monitored” design to lower risk of injury.

Any surgery brings with it risk, both to the patient and the surgeon. However, laparoscopic surgery sometimes brings an additional invisible risk: stray energy burns. Electrosurgical devices and laparoscopic instruments can suffer insulation failures and capacitive coupling, potentially causing stray energy burns to the patient. Often these burns occur out of sight of the surgeon and may go unnoticed until the patient presents with symptoms like peritonitis or sepsis.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Medical, Lasers & Laser Systems, Photonics, Robotics, Lasers, Lasers, Surgical procedures, Risk management, Injuries
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Ultra-Miniature Image Sensor

A wafer-level camera operates at low power and may be customized for application needs, which include endoscopy, surgical robots, and 3D model generation.

Minimally invasive surgery has increasingly required imaging devices to have the smallest possible dimensions but also deliver high-resolution vision capabilities. There has also been a rising demand for disposable medical devices. With these criteria in mind, in 2004, the first prototype of the NanEye sensor was created in the lab. The miniature 0.25 mm2 camera module measured 0.5 mm × 0.5 mm, with 140 × 140 pixels at a frame rate of 40 frames/second.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Diagnostics, Medical, Sensors, Imaging, Imaging and visualization, Sensors and actuators, Imaging, Imaging and visualization, Sensors and actuators, Medical equipment and supplies, Surgical procedures
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Motion Artifact Extraction Technology for Non-Invasive Blood Pressure Measurement

A module employs highly complex pulse matching criteria and analysis tools and is suitable for challenging clinical environments.

Non-Invasive Blood Pressure (NIBP) is a widely used vital sign for cardiovascular assessment. Vital signs monitors obtain a non-invasive blood pressure measurement through the use of commercially available OEM blood pressure modules incorporated into their devices. These devices typically employ the oscillometric technique for the determination of blood pressure. NIBP devices approved for clinical use are tested for compliance to standards, including the AAMI/ANSI SP10-2002.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Medical, Patient Monitoring, Software, Measurements, Sensors and actuators, Sensors and actuators, Cardiovascular system, Medical equipment and supplies
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Corneal Endothelium Delivery Instrument

A single-use, disposable device implants donor allograft tissue during endothelial keratoplasty.

Corneal endothelial failure is a common cause of corneal transplants. According to the Eye Bank Association of America, transplant tissue distributed for endothelial keratoplasty accounted for 18,221 (43%) of all keratoplasties performed in the US during 2009. Fuchs dystrophy, “other” causes, and post-cataract surgery edema were identified as the leading indications for endothelial replacement surgery. The leading indicator, Fuchs endothelial dystrophy, is an inheritable genetic condition that results in loss of endothelial cells and formation of an abnormal extracellular matrix.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Implants & Prosthetics, Medical, Body regions, Prostheses and implants, Surgical procedures
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Software for Image Contrast Enhancement

This technique provides detail and edge contrast enhancement, latitude reduction, and noise reduction when applied to digitizers for X-ray imaging.

Whenever images are acquired with a large dynamic range, a problem arises in reproducing these images on a medium (i.e. CRT, paper). There are the restrictions of the recording apparatus (number of reproducible intensity levels, color gamut, and color resolution) as well as environmental factors (flare, light level).

Posted in: Briefs, MDB, Briefs, Bio-Medical, Diagnostics, Medical, Software, Computer software / hardware, Computer software and hardware, Imaging, Imaging and visualization, Computer software / hardware, Computer software and hardware, Imaging, Imaging and visualization, Displays, Displays
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Highly Sensitive Micro Fluorescence Detector for Bioanalytical Devices

This development represents an advancement in the field of portable microfluidic analysis systems, or lab-on-a-chip devices.

An advanced micro fluorescence detector (microFD) uses a hydrogenated amorphous silicon (a-Si:H) photodiode for high sensitivity biochemical analyses in micro-capillary electrophoresis (microCE) applications, representing an advancement in the field of portable microfluidic analysis systems, or lab-on-a-chip devices. The detector is highly sensitive to the emission wavelengths of commonly used fluorescent dyes, and in an integrated configuration using a Vertical Cavity Surface Emitting Laser (VCSEL) diode, proves efficacious for heavily multiplexed microfluidic biochemical analyses. This design can be fabricated and integrated at a low cost, making it ideal for the production of portable bioanalyzers that handle minute quantities of fluids (picoliters to nanoliters), as well as emerging large-scale integrated microfluidic technologies.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Diagnostics, Medical, Patient Monitoring, Lasers, Sensors and actuators, Lasers, Sensors and actuators, Diagnosis, Fluids and secretions, Medical equipment and supplies
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