Tech Exchange

Paracellular Drug Delivery Through Baker’s Yeast Microcapsules

Yeast has the ability to reversibly open up the junctions between cells to aid drug delivery. By micro-encapsulating active ingredients inside the yeast cells, this technology enhances paracellular movement of active ingredients in mucus-rich areas such as buccal, oral, nasal, vaginal, anal, and others. Application could be by means of powder, tablet, capsule, chewable tablet, chewing gum, melting film strip, spray, cream, or gel. Yeast offers an alternative to chitosan as a permeation enhancer and mucoadhesive mechanism.

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High-Performance CIGS Solar Cell Saves Resources

AIST has developed a thin-film technology that can reduce the consumption of raw selenium below one-tenth of the conventional standard when manufacturing non-silicon-based copper-indium- gallium- selenide (CIGS) thin-film solar cells. The technology uses radio-frequency- cracked selenium radicals instead of conventional vaporized selenium, enhancing the conversion efficiency of a solar cell, and results in cells of reproducible quality from run to run. Additionally, the technology uses a black metal electrode and a light-absorbing layer containing zinc oxide. This brings about a great advancement for mass production of high-performance CIGS modules.

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Microbial-Based Lawn-Care, Pond-Care, and Cleaning Technologies

Proprietary microbial systems use naturally occurring microbes in lieu of chemicals in fertilizers, microbial inoculants, cleaning products, and pond treatments. Products are based on incorporating beneficial micro-organisms with a variety of task-specific organic surfactants, microbial nutrients, fertilizers, cleaning agents, and bio-polymers. The micro-organisms produce enzymes that continue to work even after cleaning, or — in the case of lawn and pond care — continue to make the soil or pond healthier even after fertilizing the plants or inoculating the water.

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Analytical Technique for Healthcare and Industrial Applications

Aria Analytics is commercializing a novel analytical technology to characterize liquids for healthcare and industrial applications. As a drop of liquid evaporates on the vibrating quartz sensor, it undergoes distinctive phase changes representing the unique chemical and physical characteristics of the sample. This unique “fingerprint” represents information that is not readily available from any combination of analytical methods currently in use.

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Finger Seals Replace Brush or Labyrinth Seals

Finger seals are non-contact fluid seals similar in purpose to labyrinth or brush seals in that they act as a barrier between two areas of the same or different pressures, but allow a rotating shaft to penetrate through them from one side to the other. Applications include sealing rotating parts in turbine engines, pumps, rotating air motors, or other applications where a shaft needs to be sealed against incursion or excursion of oil, air, water, or other gases or fluids.

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Unique DNA Signature Identifies Organism’s Species

Unique genetic markers called oligonucleotides can provide swift identification of a known organism or rule out an organism from known genomes. This software technology provides a way to generate thousands of such markers and provides a searchable database of chromosomal sequences for over 100 pathogens and near-neighbor organisms, unique plasmid sequences, and markers for virulence and antibioticresistant genes in a platform-independent format. Using the technology, the existing database can be extended to any DNA-based organisms. With as few as 20 DNA fragments, the system can achieve a 99% confidence of no false negatives against a library of samples.

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High-Production Suction Head for Mud, Sludge, and Sewerage Dredging

This technology features a uniquely designed suction head that eliminates problems typically experienced in alluvial diamond mining, mud, sewerage pumping, or dredging operations. This patented system offers a proven solution where no divers are required, and which can be operated from the deck of the ship in the shallow, mid-water, and deep-water operations for 24 hours a day — even on foul weather days.

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