Tech Exchange

Chemical Analysis without Reagents

A portfolio of technologies applies mid-infrared spectroscopy to the analysis of fluids. Any fluid can be analyzed, including blood, serum, and other biological fluids. Tests are non-destructive. The techniques require no reagents or other chemicals, and thus there are no chemicals to store or dispose of. The spectroscopic signatures obtained from the samples can be used to aid the diagnosis of disease, among other applications, because molecular signatures are unique. The technique has a high sensitivity to the conformation of the molecule: shape, folding, symmetry, and its state.

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Rapid DC Magnetron Sputtering

DC magnetron sputtering provides a very durable and stable coating that has many high-energy laser (HEL) and industrial applications, especially in producing coatings for high-reflectivity (HR) mirrors and anti-reflection (AR) coated windows. However, the DC magnetron sputtering deposition process is extremely slow. This slow deposition results in long coating run times that translate into increased coating cost. An organization wants to reduce magnetron sputtering deposition times from 17 hours to 2 or 3 hours, while meeting current coating performance requirements. Coatings must meet MIL-C- 48497A environmental requirements.

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Low VOC Binder/Resin System

Technology is required to reduce volatile organic compounds (VOCs) in binder/resins while maintaining or enhancing existing product properties. Potential solutions could include the addition of a compound or additive that reduces VOC demand, a new crosslinking system for polymers to enhance molecular network formation, or another technical solution that eliminates the existing issues with the low VOC resins currently available, such as poor appearance and high viscosity during drying (as typically encountered in a water borne approach), or slow drying and high application viscosity (as typically encountered in high-solids paints).

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Laser Drilling of Ceramic Composites to Form Smooth-Walled Holes

Attempts to mechanically drill high-temperature ceramic components can doom them to failure. Even laser drilling can compromise the surface oxidation layer that protects the composite part in high- temperature service.

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Molecular Vaccine for Prophylaxis and Treatment of Listeriosis

Biomedical Center in Moscow has developed a peptide formulation that induces activation and proliferation of the cytotoxic lymphocyte’s (CTL) clones and enables them to recognize and selectively kill Listeria infected cells. As the lifetime of CTL clones is 3 to 7 years or more the formulation could be used for both prophylaxis and treatment. The developer is looking for support/collaboration to implement the following three stages: promoting the peptide preparation as a veterinarian vaccine; promoting the peptide preparation as human vaccine; and promoting the peptide preparation in Europe and other markets.

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Solar-Based Hydrogen Generation Technology

A company seeks to increase the efficiency of solar-based hydrogen generation systems by device technologies that can help to develop a new module with at least 16% solar energy utilization efficiency. Examples include the Z-scheme method and tandem type, which has achieved a Solar Energy Utilization Efficiency of 4.5% and 12.4%, respectively. Of particular interest are research organizations such as universities, and venture organizations that work jointly with them.

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Making Metal Packaging Lighter

Because of increasing cost pressures on high-volume metal packaging, a manufacturer needs to make each unit weight of metal (steel and aluminum) go further. Technologies are sought that make metal packaging lighter and enhance the physical performance (like tensile strength, stiffness, etc). This could include, for example, improvements brought about by “dimpling” the metal surface and other macro surface modifications.

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Diagnostic Pattern Recognition Using Mid-IR Spectroscopy

By applying mid-infrared spectroscopy to bodily fluids, this suite of technologies offers the potential for quick, accurate, and inexpensive diagnostic support for a variety of diseases in humans or animals. Every disease or condition results in quantitative imbalances in the “normally occurring” molecules of the body — raised glucose or cholesterol, for example. Pathogens like bacteria and viruses contribute their own molecular loads as well as destabilizing the body’s “homeostasis;” its usual stable and healthy condition. A spectrographic “snapshot” of sample fluids from blood serum, lymph, and saliva can be matched to the unique spectroscopic pattern of known conditions and diseases. Pattern recognition can then result in a quick diagnosis.

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Precision Feedback-Controlled Laser Drilling for Fluid Flow Apertures

This technology provides a method of laserdrilling any component under the control of real-time feedback to provide for predictable, calibrated fluid flow through one or an array of holes formed in the component. The technique can improve flow control through a machined part by an order of magnitude or more over conventional open-loop laser drilling technologies, increasing the predicted lifetime of component parts. The method can be applied to any component or device that requires controlled flow of any fluid.

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High-Birefringence Optical Material

A high-birefringence optical material suitable for implementation in optical systems is sought. This material has several qualities of interest beyond high birefringence: high hardness, making it amenable to standard polishing and manufacturing processes; low CTE (coefficient of thermal expansion); low CTRI (coefficient of thermal refractive index); low absorption at 1.55 micrometers; and reasonable bulk density. A material is sought that can be processed and handled using standard techniques.

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