Special Coverage

Clamshell Sampler
Shape Memory Alloy Rock Splitter
Deployable Extra-Vehicular Activity Platform (DEVAP) for Planetary Surfaces
2016 Create The Future Design Contest Open For Entries
The Future of Exploration Starts With 3D Printing
Home

Functionalized Patterning of Tissue Engineering Substrates

Task also includes bioprinting cell-laden constructs for multi-compartment tissue chambers. Lyndon B. Johnson Space Center, Houston, Texas Tissue engineering (TE) is an emerging field for tissue repair and regeneration compared to conventional techniques including autograft and allograft, through engineering functional implants created from living cells. TE is a highly interdisciplinary research area where material science, engineering, and biology are blended to achieve tissue regeneration. Efforts have been made to regenerate liver, skin, bone, and vascular tissues by applying a tissue engineering approach. To generate any type of tissue in a laboratory environment, scientists need to mimic the cellular microenvironment by offering structural, chemical, physical, and biological cues to the cells. Introduction of these cues to the cellular environment starts with manufacturing a supportive matrix called a scaffold.

Posted in: Briefs, TSP

Read More >>

Hearing Test System Suitable for Self-Administered Hearing Assessment

Lyndon B. Johnson Space Center, Houston, Texas Astronauts have developed hearing loss in space, so the goal of this project was to provide a robust, self-administered, accurate noise-tolerance hearing test system for astronauts. The device includes Bekesy-like threshold audiometry, distortion product otoacoustic emission testing, and gap-detection testing.

Posted in: Briefs, TSP

Read More >>

Assessment of Microbial Bioburden Within Aerogel Matrices

A post-capture aerogel degradation via cryogenic grinding is compatible with downstream nucleic-acid-based molecular modes of analysis. NASA’s Jet Propulsion Laboratory, Pasadena, California A makeshift apparatus has been designed composed of a sealed, hydrophobic 2-propanol/SiO2 aerogel component to filter outside air particles. Following verification and assessment, the apparatus was crafted with a Buchner funnel. Aerogel matrices were tightly fitted into filter housings and secured in side-arm flasks, which were then equipped to a vacuum pump to pull air through the aerogel matrices. Aerogels, both with and without fiberglass reinforcement, were used to collect airborne particulates for one- and three-hour increments. An untreated negative control aerogel, employing air collection from a laminar hood, and a positive aerogel matrix were seeded with endospores that verified the extraction from the matrices.

Posted in: Briefs, TSP

Read More >>

The Dusk of Fire-Wire, The Dawn of USB 3.0: Advancements and critical aspects of camera interfaces for next generation vision systems

Before 2011, many system designs were built on the most popular interface at the time: FireWire. This technology is slowly becoming obsolete and is commonly being replaced by USB 3.0, the new predominant interface for industrial and scientific cameras. In this paper we will outline why people are making the upgrade from FireWire to the USB 3.0 interface, and why USB 3.0 is here to stay.

Posted in: White Papers, Optics, Photonics

Read More >>

Universal Cell-Directed Nanotheranostics

A modified stem cell includes a micro or nano particle-based delivery system. Lyndon B. Johnson Space Center, Houston, Texas The present invention relates to the field of nanotechnology and, more particularly, to the field of delivery of active agents such as therapeutic and/or imaging agents using micro/nanoscale particles. Porous particles, such as porous silicon particles and porous silica particles, have a number of applications including use as drug delivery carriers. A need exists to develop new types of porous particles and new methods of using them for the treatment of diseases such as cancer.

Posted in: Briefs

Read More >>

Fluid Preservation System (FPS)

This system can be used by first responders during natural disasters. Lyndon B. Johnson Space Center, Houston, Texas Biological samples contain labile molecules that deteriorate rapidly ex-vivo. Terrestrially, biological samples are preserved either by freezing them (–80 °C) or by including preservation chemicals. While chemical preservation may be ideal for certain molecules, their functionality is selective and can, while preserving one set of molecules, damage others. Refrigeration poses major logistical challenges of power and logistics. These two options pose major cost and logistics burdens to NASA as they continue to collect biological specimens during flight. Although the International Space Station (ISS) includes a refrigerator to preserve samples, there are no such capabilities aboard return vehicles, especially unmanned vehicles. Furthermore, it should be noted that payloads that are dropped off in remote locations often are recovered after many days, making the biological samples extremely vulnerable to ambient conditions, often rendering them useless.

Posted in: Briefs

Read More >>

Using Electromagnetic Time-Variance Magnetic Fields to Generate and Re-Grow Cartilage

Lyndon B. Johnson Space Center, Houston, Texas Adevice provides electromagnetic pulses at a predetermined frequency that will result in cartilage cell regeneration and regrowth for patients with arthritis, which reduces or eliminates joint cartilage. The device can be wrapped around the joints in a patient where infected cartilage is located. Molecular and marker data have shown this innovation to work as described above. This is a non-invasive technology that regenerates the patient’s own tissue, allowing for possibly no significant side-effects or foreign matter reactivity.

Posted in: Briefs, TSP

Read More >>

The U.S. Government does not endorse any commercial product, process, or activity identified on this web site.