Special Coverage


Cryogenic Grinding for Mechanical Abrasion for Hardy Endospores

The method is far superior to conventional mechanical abrasion strategies. NASA’s Jet Propulsion Laboratory, Pasadena, California A comparative analysis was carried out between an emerging cryogenic grinding method and a conventional wet-chemistry/bead-beating endospore disruption approach. After extensive trial and error, it was determined that a regimen of three cryogenic grinding cycles of 2 minutes each was optimum for downstream DNA recovery. Spores embedded in ice exhibited a mere 1-log reduction in recovery following cryo-milling for up to 30 minutes. The observed total spore-borne DNA recovery was quite impressive, as well established, streamlined techniques for extracting DNA from endospores typically recover, at best, ≈10% of the molecules present. To facilitate the nucleic-acid-based testing required to detect and quantify DNA and endospores recovered, this innovation implements cryogenic grinding procedures followed by qPCR (quantitative polymerase chain reaction) methods to verify this novel capture technique.

Posted in: Briefs


Making Mesh Buckypaper Capsules for Transplantation of Cells and Implantation of Medical Devices

Applications include gene therapy, cell transplantation for treatment of diabetes and other disorders, and improved biocompatibility of implantable medical devices. Ames Research Center, Moffett Field, California The innovation consists of a method for fabricating containers (“biocapsules”) made of biocompatible mesh for holding living cells and tissues, to facilitate transplantation into the body, for a wide range of high-impact medical applications. The biocompatible mesh (buckypaper) is made of carbon nanotubes (CNTs), and the containers are fabricated by depositing the nanotubes onto pre-formed molds, in order to achieve the desired shape and size of the biocapsule. Various forms are possible, including hollow tubes, closed cylinders, and more complex shapes, determined by the configuration of the mold. The biocompatibility of the capsule makes it possible to implant a variety of cells into a host, even cells that would otherwise be considered “foreign,” such as cells from unmatched donors, specially engineered cells, and even nonhuman cells. Because the capsule pores are too small for the cells to pass, the cells stay inside the capsule, where they are protected from the host immune system. The pores of the biocapsule permit gas exchange (oxygen, carbon dioxide), as well as free diffusion of metabolites, which keeps the cells healthy. Tissue or tissue fragments, and micro- or nano-scale medical devices can also be placed inside the biocapsule to facilitate their implantation into the body.

Posted in: Briefs


Prosthetic Arm Controlled by Imagining a Motion

Controlling a prosthetic arm by just imagining a motion may be possible through the work of Mexican scientists at the Centre for Research and Advanced Studies. First, it is necessary to know if there is a memory pattern in the amputee's brain in order to know how the arm moved. The pattern is then translated to instructions for the prosthesis.

Posted in: News, Electronics, Implants & Prosthetics, Rehabilitation & Physical Therapy


Secret of Eumelanin’s Ability to Absorb Broad Spectrum of Light Uncovered

Melanin — and specifically, the form called eumelanin — is the primary pigment that gives humans the coloring of their skin, hair, and eyes. It protects the body from the hazards of ultraviolet and other radiation that can damage cells and lead to skin cancer. But the exact reason why the compound is so effective at blocking such a broad spectrum of sunlight has remained something of a mystery. Now, however, researchers at MIT and other institutions have solved that mystery, potentially opening the way for the development of synthetic materials that could have similar light-blocking properties.

Posted in: News, Solar Power, Composites, Optics, Photonics


'Active' Surfaces Control How Particles Move

Researchers at MIT and in Saudi Arabia have developed a new way of making surfaces that can actively control how fluids or particles move across them. The work might enable new kinds of biomedical or microfluidic devices, or solar panels that could automatically clean themselves of dust and grit.The system makes use of a microtextured surface, with bumps or ridges just a few micrometers across, that is then impregnated with a fluid that can be manipulated — for example, an oil infused with tiny magnetic particles, or ferrofluid, which can be pushed and pulled by applying a magnetic field to the surface. When droplets of water or tiny particles are placed on the surface, a thin coating of the fluid covers them, forming a magnetic cloak.The thin magnetized cloak can then actually pull the droplet or particle along as the layer itself is drawn magnetically across the surface. Tiny ferromagnetic particles, approximately 10 nanometers in diameter, in the ferrofluid could allow precision control when it’s needed — such as in a microfluidic device used to test biological or chemical samples by mixing them with a variety of reagents. Unlike the fixed channels of conventional microfluidics, such surfaces could have “virtual” channels that could be reconfigured at will.The new approach could be useful for a range of applications: For example, solar panels and the mirrors used in solar-concentrating systems can quickly lose a significant percentage of their efficiency when dust, moisture, or other materials accumulate on their surfaces. But if coated with such an active surface material, a brief magnetic pulse could be used to sweep the material away.Source Also: Read more Materials tech briefs.

Posted in: News, Renewable Energy, Solar Power, Drug Delivery & Fluid Handling, Fluid Handling


Discover The Advantages Of Pure Fused Silica Capillary Tubing In Medical Applications

A wide range of medical devices incorporate tubing for the controlled delivery of therapeutic agents. Other devices employ capillary tubing for mass flow control of ancillary fluids and gases where the rate of delivery is of critical importance to the particular medical procedure. In this white paper, Molex explores the special advantages of pure fused silica tubing in medical applications; including what makes it unique, specific design advantages, how it compares to metal and PEEK tubing, and more. Read it now!

Posted in: Tubing/Extrusion, White Papers, White Papers


New Technology Detects Bacterial Pathogens in Soldiers' Combat Wounds

A biological detection technology developed by Lawrence Livermore National Laboratory scientists can detect bacterial pathogens in the wounds of U.S. soldiers that have previously been missed by other technologies. This advance may, in time, allow an improvement in how soldiers' wounds are treated.

Posted in: News, Detectors, Sensors