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Regulating Glucose and pH, and Monitoring Oxygen in a Bioreactor

Glucose and oxygen concentrations are monitored, and glucose concentration and pH are adjusted as needed. Figure 1 is a simplified schematic diagram of a system that automatically regulates the concentration of glucose or pH in a liquid culture medium that is circulated through a rotating-wall perfused bioreactor. Another system, shown in Figure 2, monitors the concentration of oxygen in the culture medium.

Posted in: Medical, Briefs

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Implantable Wireless MEMS Sensors for Medical Uses

Sensors designed and fabricated according to the principles of microelectromechanical systems (MEMS) are being developed for several medical applications in outer space and on Earth.The designs of these sensors are based on a core design family of pressure sensors, small enough to fit into the eye of a needle, that are fabricated by a “dissolved wafer” process. The sensors are expected to be implantable, battery-less, and wireless. They would be both powered and interrogated by hand-held radio transceivers from distances up to about 6 in. (about 15 cm). One type of sensor would be used to measure blood pressure, particularly for congestive heart failure. Another type would be used to monitor fluids in patients who have hydrocephalus (high brain pressure). Still other types would be used to detect errors in delivery of drugs and to help patients having congestive heart failure.

Posted in: Medical, Briefs

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Dehydrating and Sterilizing Wastes Using Supercritical CO2

A relatively low-temperature process for dehydrating and sterilizing biohazardous wastes in an enclosed life-support system exploits (1) the superior mass-transport properties of supercritical fluids in general and (2) the demonstrated sterilizing property of supercritical CO2 in particular. The wastes to be treated are placed in a chamber. Liquid CO2, drawn from storage at a pressure of 850 psi (˜5.9 MPa) and temperature of 0 °C, is compressed to pressure of 2 kpsi (˜14 MPa) and made to flow into the chamber. The compression raises the temperature to 10 °C. The chamber and its contents are then further heated to 40 °C, putting the CO2 into a supercritical state, in which it kills microorganisms in the chamber. Carrying dissolved water, the CO2 leaves the chamber through a back-pressure regulator, through which it is expanded back to the storage pressure. The expanded CO2 is refrigerated to extract the dissolved water as ice, and is then returned to the storage tank at 0 °C.

Posted in: Bio-Medical, Medical, Briefs

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Multiaxis, Lightweight, Computer-Controlled Exercise System

This system offers unprecedented versatility for physical conditioning and evaluation The multipurpose, multiaxial, isokinetic dynamometer (MMID) is a computer-controlled system of exercise machinery that can serve as a means for quantitatively assessing a subject’s muscle coordination, range of motion, strength, and overall physical condition with respect to a wide variety of forces, motions, and exercise regimens. The MMID is easily reconfigurable and compactly stowable and, in comparison with prior computer-controlled exercise systems, it weighs less, costs less, and offers more capabilities.

Posted in: Medical, Briefs

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Production of Tuber-Inducing Factor

This substance regulates the growth of potatoes and some other plants. A process for making a substance that regulates the growth of potatoes and some other economically important plants has been developed. The process also yields an economically important by-product: potatoes.

Posted in: Medical, Briefs

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Vacuum-Assisted, Constant- Force Exercise Device

An important advantage over other exercise machines would be light weight.

Posted in: Medical, Briefs

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Studying Functions of All Yeast Genes Simultaneously

This method could accelerate research on treatment of some diseases.

Posted in: Medical, Briefs, TSP

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