A report describes an experimental study of whether an advanced fiber-optic dynamic-light-scattering (DLS) probe affords a capability for noncontact detection of particles of various sizes associated with the stages of growth of protein crystals in automated hanging-drop protein-growth apparatuses. [A related previous report was described in "DLS Sizing of Particles in Hanging Liquid Drops" (LEW-16515),NASA Tech Briefs, Vol. 21, No. 12 (December 1997), page 98.] The DLS probe used in this study was a modified version of the one described in "Compact, Noncontact Fiber-Optic Probe for Diagnosis of Eye Diseases" (LEW-16429), NASA Tech Briefs, Vol. 22, No. 2 (February 1998), page 82, and was augmented with a miniature microscope for viewing protein crystals.

This work was done by Rafat R. Ansari of Case Western Reserve University; Kwang I. Suh of the National Research Council; Lawrence J. DeLucas, Alireza Arabshahi, and Terry L. Bray of the University of Alabama at Birmingham; and W. William Wilson of Mississippi State University for Lewis Research Center.

Inquiries concerning rights for the commercial use of this invention should be addressed to

NASA Lewis Research Center
Commercial Technology Office
Attn: Tech Brief Patent Status
Mail Stop 7~3
21000 Brookpark Road
Ohio 44135

Refer to LEW-16611.

NASA Tech Briefs Magazine

This article first appeared in the October, 1998 issue of NASA Tech Briefs Magazine.

Read more articles from the archives here.