Technology Eliminates the Need for Pre-Wetting Cartridge Filters

There has been a long-term need in the filtration industry — particularly for a variety of life science applications — to eliminate the need for pre-wetting cartridge filters with alcohol before sending them to customers. It is not only an expensive, time-consuming process, but it also increases the risk of bacterial contamination.

Posted in: Briefs, MDB, Briefs, Manufacturing & Prototyping, Bio-Medical, Medical, Bacteria, Medical equipment and supplies, Coatings Colorants and Finishes, Coatings, colorants, and finishes, Materials properties
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Quantifying Risk in Various Methods of Continuous Monitoring

Worldwide, there is growing concern about how to protect public safety and increase cooperation among regulatory agencies to audit medical device companies and their suppliers. Regulatory agencies are increasingly looking to global organizations such as the Global Health Task Force (GHTF) to adopt harmonization in regulatory practices. As recent as August 2010, the GHTF made medical device suppliers inclusive of site auditing guidelines. (“A supplier delivering materials, components, or services, that may influence the safety and performance of the product.” GHTF/SG4/N33)

Posted in: Briefs, MDB, Briefs, Imaging, Bio-Medical, Medical, Patient Monitoring, Medical equipment and supplies, Risk management, Risk assessments, Safety regulations and standards
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High-Performance Micro-Porous Fluoropolymer Plastics for Critical Applications

Polytetrafluoroethylene (PTFE) is a fully fluorinated polymer with exceptional chemical and physical properties: excellent chemical resistance, high temperature stability, good dielectric and nonstick properties and exceptional resistance to degeneration under severe conditions.

Posted in: Briefs, MDB, Briefs, Coatings & Adhesives, Materials, Bio-Medical, Medical, Chemicals, Heat resistant materials, Materials properties, Plastics
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Cytometer on a Chip

A cytometer now under development exploits spatial sorting of sampled cells on a microarray chip followed by use of grating-coupled surface-plasmon-resonance imaging (GCSPRI) to detect the sorted cells. This cytometer on a chip is a prototype of contemplated future miniature cytometers that would be suitable for rapidly identifying pathogens and other cells of interest in both field and laboratory applications and that would be attractive as alternatives to conventional flow cytometers.

Posted in: Briefs, MDB, TSP, Briefs, TSP, Bio-Medical, Medical, Patient Monitoring, Integrated circuits, Integrated circuits, Diagnosis, Materials identification
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Enabling Disabled Persons To Gain Access to Digital Media

A report describes the first phase in an effort to enhance the NaviGaze software to enable profoundly disabled persons to operate computers. (Running on a Windows-based computer equipped with a video camera aimed at the user’s head, the original NaviGaze software processes the user’s head movements and eye blinks into cursor movements and mouse clicks to enable hands-free control of the computer.) To accommodate large variations in movement capabilities among disabled individuals, one of the enhancements was the addition of a graphical user interface for selection of parameters that affect the way the software interacts with the computer and tracks the user’s movements. Tracking algorithms were improved to reduce sensitivity to rotations and reduce the likelihood of tracking the wrong features. Visual feedback to the user was improved to provide an indication of the state of the computer system. It was found that users can quickly learn to use the enhanced software, performing single clicks, double clicks, and drags within minutes of first use. Available programs that could increase the usability of NaviGaze were identified. One of these enables entry of text by using NaviGaze as a mouse to select keys on a virtual keyboard.

Posted in: Briefs, TSP, Bio-Medical, Medical, Computer software / hardware, Computer software and hardware, Computer software / hardware, Computer software and hardware, Diseases, Human machine interface (HMI), Kinematics
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Microgravity-Enhanced Stem Cell Selection

Stem cells, both embryonic and adult, promise to revolutionize the practice of medicine in the future. In order to realize this potential, a number of hurdles must be overcome. Most importantly, the signaling mechanisms necessary to control the differentiation of stem cells into tissues of interest remain to be elucidated, and much of the present research on stem cells is focused on this goal. Nevertheless, it will also be essential to achieve large-scale expansion and, in many cases, assemble cells in 3D as transplantable tissues. To this end, microgravity analog bioreactors can play a significant role.

Posted in: Briefs, MDB, TSP, Briefs, TSP, Bio-Medical, Medical, Biological sciences, Medical equipment and supplies, Identification
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Diagnosis and Treatment of Neurological Disorders by Millimeter-Wave Stimulation

Increasingly, millimeter waves are being employed for telecomm, radar, and imaging applications. To date in the U.S, however, very few investigations on the impact of this radiation on biological systems at the cellular level have been undertaken. In the beginning, to examine the impact of millimeter waves on cellular processes, researchers discovered that cell membrane depolarization may be triggered by low levels of integrated power at these high frequencies. Such a situation could be used to advantage in the direct stimulation of neuronal cells for applications in neuroprosthetics and diagnosing or treating neurological disorders.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Medical, Diagnosis, Nervous system
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Tear-Based Glucose Sensor for Diabetes Monitoring

Diabetic control typically requires daily monitoring of blood glucose levels. This involves finger pricking 2–10 times a day in order to obtain a sample for assay. Many find the finger prick tedious or painful and fall into noncompliance. Others may also dislike the assorted “paraphernalia” that must be carried around. Research into the “next-tech” for diabetes care has led many researchers to investigate tear glucose sensing as an alternative. As promising as many of these devices are, they are many years from market. Here the development of a near market tear glucose sensor is reported.

Posted in: Briefs, MDB, Briefs, Bio-Medical, Medical, Patient Monitoring, Sensors, Sensors and actuators, Sensors and actuators, Diseases, Fluids and secretions, Medical equipment and supplies, Test equipment and instrumentation
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Maintaining Sterility Assurance Level in Medical Device Design

A medical device undergoing design and classified as sterile will be confronted with various obstacles, not the least of which is how to determine and maintain its proposed Sterility Assurance Level (SAL) as it approaches its ultimate goal: delivery to market.

Posted in: Briefs, MDB, Briefs, Manufacturing & Prototyping, Bio-Medical, Medical, Bacteria, Medical equipment and supplies, Risk management, Fabrication, Safety regulations and standards
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Electrocardiography (ECG) Necklace

Integrated wearable monitoring systems based on body area networks (BANs) enable continuous, reliable, and long-term monitoring of physio- and biological signals on the move, leading to wearable health solutions for next-generation healthcare, wellness, and lifestyle. An electrocardiography (ECG) necklace has been developed to target the simultaneous monitoring of cardiac and physical activity in everyday life situations.

Posted in: Briefs, MDB, Briefs, Electronics, Electronics & Computers, Bio-Medical, Medical, Patient Monitoring, Electronic equipment, Electronic equipment, Cardiovascular system, Medical equipment and supplies
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