Topics

Health, Medicine, & Biotechnology

Briefs : Materials
Repeatable, Low-Cost UV Assembly of Biosensors

A biosensor is an analytical device that converts a biological response into an electrical signal. It is increasingly being used as a cost-effective diagnostic tool that offers the capability to render efficient, easy-to-use, and accurate diagnosis. While technological advances in biosensors are...

Briefs : Medical
Tethered Endoscope for Photographing the Esophagus

Conventional endoscopes are the “gold standard” for investigating and evaluating mucosal disease of the esophagus. Free-swimming camera pills are large because they must carry camera, batteries, memory, illumination, and some level of image processing power on board. A typical camera pill...

Briefs : Medical
Isolation of the 'Paenibacillus phoenicis', a Spore-Forming Bacterium

A microorganism was isolated from the surfaces of the cleanroom facility in which the Phoenix lander was assembled. The isolated bacterial strain was subjected to a comprehensive polyphasic analysis to characterize its taxonomic position. Both phenotypic and phylogenetic...

Briefs : Medical
Cell Radiation Experiment System

The cell radiation experiment system (CRES) is a perfused-cell culture apparatus, within which cells from humans or other animals can (1) be maintained in homeostasis while (2) being exposed to ionizing radiation during controlled intervals and (3) being monitored to determine the effects of radiation and the...

Briefs : Imaging
Monolithically Integrated, Mechanically Resilient Carbon-Based Probes for Scanning Probe Microscopy

Scanning probe microscopy (SPM) is an important tool for performing measurements at the nanoscale in imaging bacteria or proteins in biology, as well as in the electronics industry. An essential element of SPM is a sharp, stable tip that possesses...

Articles : Medical
2010 Create the Future Design Contest Medical Category Winner

(Winner of an HP Workstation)

IDEA Enhanced Pulse Oximetry

Rodrigo Teixeira, Alton Reich, and Stephen Malin

Huntsville, AL

Stroke volume, or how much volume of blood the heart pumps with each beat, demonstrates the organ’s efficiency...

Briefs : Materials
Ultra-High-Molecular-Weight Polyethylene Technology for Minimally Invasive Devices

Ultra-high-molecular-weight polyethylene (UHMWPE) has been used for decades as a biomaterial in joint replacements. Recently, this technology was refined to serve the needs of minimally invasive surgical applications, particularly cardiovascular implants. UHMWPE...

Briefs : Medical
Circulatory Assist Pump for Implantable Artificial Heart Device

When a patient’s heart disease cannot be treated, heart transplantation is required, but only a few people can receive transplants. These rare opportunities for transplantation have created a demand for artificial hearts.

Features : Sensors/Data Acquisition
Ultrasonic Echo Probe With Measurement of Contact Pressure Distribution

This ultrasonic echo apparatus can measure tissue inside living bodies, non-invasively. The developed probe has a film-like piezoelectric sensor installed on the contact surface of an ordinary medical ultrasonic probe, and it can measure the contact pressure distribution...

Briefs : Medical
Modifying Polyethylene Oxide for Melt-Processability

Generally, high-molecular-weight polyethylene oxide (PEO) can present processing challenges due to its high melt viscosity and poor melt drawability; it can be difficult to form into fine-gauge film or small-diameter fibers. There is the alternative technology of solution casting, which has...

Briefs : Materials
Topical Compositions and Glove for Protection and Shielding Against Radiation Exposure

Over the past several decades, there has been a proliferation of medical diagnostic and treatment devices that involve the use of X-rays, beta rays, gamma rays, and radioactive isotopes. In addition, there has been recent concern regarding possible radiation...

Briefs : Materials
Digital Microfluidics Sample Analyzer

Three innovations address the needs of the medical world with regard to microfluidic manipulation and testing of physiological samples in ways that can benefit point-of-care needs for patients such as premature infants, for which drawing of blood for continuous tests can be life-threatening in their own...

Briefs : Medical
Process to Selectively Distinguish Viable From Non-Viable Bacterial Cells

The combination of ethidium monoazide (EMA) and post-fragmentation, randomly primed DNA amplification technologies will enhance the analytical capability to discern viable from non-viable bacterial cells in spacecraft-related samples. Intercalating agents have been widely...

Briefs : Medical
Radiation Protection Using Carbon Nanotube Derivatives

BHA and BHT are well-known food preservatives that are excellent radical scavengers. These compounds, attached to single-walled carbon nanotubes (SWNTs), could serve as excellent radical traps. The amino-BHT groups can be associated with SWNTs that have carbolyxic acid groups via acid-base...

Briefs : Medical
Orthotic Dynamically Adjusts to Changes in Foot Structure and Movement

Kinesthotic© orthotics are made to adapt to the foot by replicating, within footwear, an explicit quality of beach-sand surface dynamics on whatever surface the footwear is used. The resulting support complies with the biomechanically sound and functional supportive...

Briefs : Medical
Reusable Personal Radiation Dosimeter for Ultraviolet or Radioactive Radiation

Radiation dosimeters are important for people working with radioactive isotopes, as in analytical research laboratories, in nuclear medical applications, in medical X-ray imaging, in nuclear power-stations, or in non-destructive testing of materials by ionizing...

Briefs : Medical
High-Altitude Hydration System

Three methods are being developed for keeping water from freezing during high-altitude climbs so that mountaineers can remain hydrated. Three strategies have been developed. At the time of this reporting two needed to be tested in the field and one was conceptual.

Briefs : Medical
Eye, Ear, and Skin Scope

A handheld, digitized ophthalmo scope, otoscope, or dermoscope takes digital images and video, and transmits the images to patients’ electronic medical records and/or to physicians for remote diagnosis. The device can be used for retinal (ophthalmoscopy), ear (otoscopy), or skin (dermatoscopy) imaging.

Briefs : Photonics/Optics
Enhancing Tumor Drug Delivery by Laser-Activated Vascular Barrier Disruption

An obstacle to successful cancer drug therapy is the existence of drug delivery barriers, which result in insufficient and heterogeneous drug delivery to the tumor tissue. This drug delivery problem not only limits the clinical application of existing chemotherapeutics,...

Briefs : Medical
Fast, Quantitative Diagnostic Reader for Multiple Medical Tests

While most physicians have easy access to lab tests, those tests can be slow and expensive. Consumer versions of tests are inaccurate and have limited scope, and often involve sending a sample to a lab. Physicians, emergency rooms, EMTs, patients, visiting nurses, and caregivers may...

Briefs : Medical
Miniature Bioreactor System for Long-Term Cell Culture

A prototype miniature bioreactor system is designed to serve as a laboratory benchtop cell-culturing system that minimizes the need for relatively expensive equipment and reagents and can be operated under computer control, thereby reducing the time and effort required of human investigators...

Briefs : Medical
Fabrication and Modification of Nanoporous Silicon Particles

Silicon-based nanoporous particles as biodegradable drug carriers are advantageous in permeation, controlled release, and targeting. The use of biodegradable nanoporous silicon and silicon dioxide, with proper surface treatments, allows sustained drug release within the target site...

Briefs : Medical
Electrochemical Detection of Multiple Bioprocess Analytes

An apparatus that includes highly miniaturized thin-film electrochemical sensor array has been demonstrated as a prototype of instruments for simultaneous detection of multiple substances of interest (analytes) and measurement of acidity or alkalinity in bioprocess streams. Measurements...

Application Briefs : Medical
Custom Assembly Helps Create Medical-Grade Saline in Space
BioConnect® bag and tubing assemblies
Cole-Parmer Instrument
Vernon Hills, IL
800-323-4340
www.coleparmer.com

BioConnect custom bag and tubing assemblies supplied the materials and services to catalyze the production of a prototype for the Intravenous...

Briefs : Medical
Zinc-Doped Tricalcium Phosphate Ceramic for Surgical Implants

A ceramic body consisting of the phases of tricalcium phosphate and/or hydroxyapatite provides biocompatibility with hard tissues. When such a ceramic body is implanted in a bone, direct connection is formed between the bone and the ceramic body without intervention of any fibrous...

Briefs : Imaging
Micro-Electrode Visual Inspection System Utilizing Image Processing Tools

A system was devised to aid in the inspection of micro-electrode assemblies utilized in clinical lab instruments to conduct impedance measurements on living cells in a 384 bottomless well casing with the electrode layer bonded to the housing, creating the closed-cell,...

Briefs : Electronics & Computers
Power-Assist Control Interface for Wheelchairs

A computer-controlled, programmable control interface allows safe, intuitive manual control for motorized wheelchairs that operate in variable terrain. The key feature of this technology is its proprietary computer program that enables an operator to manage a load as if it were light and on a smooth...

Briefs : Materials
Neuroprosthetics and Solutions for Restoring Sensorimotor Functions

Advances in body armor and life-saving technology have increased survival rates of severely injured military personnel. Unfortunately, the survivors of improvised explosive devices are often left with amputations and/or spinal cord injuries. The increase in amputations and...

Briefs : Medical
Implantable Microsystems for Anatomical Rewiring of Brain Circuitry

It has been demonstrated that after a stroke-like lesion in the cerebral cortex of non-human primates, the remaining intact tissue undergoes extensive neuro-physiological and neuroanatomical remodeling. The ability of cortical areas remote from the infarct to form new...

Briefs : Medical
Use of Recombinant Factor VIIa for Control of Combat-Related Hemorrhage

Blood loss is a major cause of death among combat casualties, accounting for nearly half of all deaths on the battlefield. The great majority of these deaths is due to intracavitary hemorrhage that cannot be controlled by traditional methods such as tourniquets or pressure...