Health, Medicine, & Biotechnology

Briefs : Medical
Methods of Manufacturing Bioactive Gels from Extracellular Matrix Material

Biologic scaffolds composed of extracellular matrix material (ECM) have been used for the repair of a variety of tissues including the lower urinary tract, esophagus, myocardium, and musculotendinous tissues, often leading to tissue-specific constructive remodeling with...

Briefs : Medical
Multi-Parameter Biodosimetric HemoDose Tools

There are continuous concerns about the possibility of nuclear and radiological terrorism or accidents that may result in mass casualties in densely populated areas. To guide medical personnel in their clinical decisions for effective medical management and treatment of exposed individuals, biomarkers...

Briefs : Medical
Soft-Tissue Emulsification Using a Mechanism of Ultrasonic Atomization Inside Gas or Vapor Cavities

The current method of emulsifying tissue employs focused ultrasound with microsecond pulses and cavitation. This invention emulsifies soft tissue using a mechanism of ultrasonic atomization inside gas or vapor cavities.

The method of...

Briefs : Medical
Relativistic Ion Tracks (RITRACKS)

Once astronauts venture beyond Earth’s protective atmosphere, they are exposed to the high-energy charged particles of galactic cosmic rays (GCR) and solar particle events (SPE), and secondary protons and neutrons. GCR are composed of ions, the great majority of which are protons (≈87%) and helium nuclei...

Briefs : Medical
Medical Oxygen Concentrator for Microgravity Operation

Supplemental oxygen delivery systems are vital to provide a critical life support respiratory function. Whether they are used for patients suffering from lung diseases or other illnesses, or astronauts donning an oxygen mask during a toxic spill or fire on a spacecraft, lightweight and...

Briefs : Medical
Lateral Displacement Device for Blood Cell Separation

Separation of particles based on size is one of the essential components in biochemical analysis, environmental assays, and industrial and biomedical applications. Filtration is one of the most frequently used techniques to separate particles. A mechanical filter can be used to remove,...

Briefs : Medical
Using a Blood Clot in Microfluidic Valving Applications

The lack of reliable microvalves impedes many lab-on-a-chip applications for blood analysis. On the other hand, blood clotting — the formation of solid blood aggregate to stop bleeding — provides a natural valving mechanism. It is therefore very attractive to use this mechanism for...

Briefs : Medical
Drug-Encapsulated Prosthetic Enhancement

This invention places a drug delivery system inside a prosthetic implant to circumvent the physical issues encountered after fitting the implant. Implants being relatively large in size would be able to house the drug-carrying device inside them without compromising the structural integrity or the...

Briefs : Medical
Portable Resting State Detection System Using Functional Near-Infrared Spectroscopy

The ability to distinguish between high and low levels of task engagement is important for detecting and preventing performance decrements during safety-critical operational tasks in the real world. Examples of such tasks include commercial aviation, monitoring...

Briefs : Medical
Ultrasound Competence Test Metrics

Diagnostic medical ultrasound requires psychomotor skill in image acquisition and cognitive skill in image interpretation. There is a lack of an objective, quantitative, and standardized method to assess psychomotor skill. In traditional radiology and cardiology training programs, physicians are certified based...

Briefs : Medical
Bayesian Sleep Fusion

To ensure mission success, astronauts must maintain a high level of performance, even when work-rest schedules result in chronic sleep restriction and circadian misalignment, both of which can contribute to fatigue and performance deficits unless effective countermeasures are used. The overarching goal of this project is to...

Briefs : Medical
Technique for Reversible Permeabilization of Live Cells for Intracellular Delivery of Quantum Dots

Nanomaterials are comparable in size to various biomolecules (1 to 100 nm), and have unique properties such as enhanced electrical conductivity, increased chemical reactivity, and novel optical properties that make them attractive candidates for...

Briefs : Medical
Introduction of Structural Affinity Handles as a Tool in Selective Nucleic Separations

This invention relates to the general field of bio-chemical separations. Current methods for separating nucleic acids either lack sufficient selectivity or large-capacity production as required for gene therapy or DNA vaccines or other applications. There is a...

Briefs : Medical
Functionalized Patterning of Tissue Engineering Substrates

Tissue engineering (TE) is an emerging field for tissue repair and regeneration compared to conventional techniques including autograft and allograft, through engineering functional implants created from living cells. TE is a highly interdisciplinary research area where material science,...

Briefs : Medical
Hearing Test System Suitable for Self-Administered Hearing Assessment

Astronauts have developed hearing loss in space, so the goal of this project was to provide a robust, self-administered, accurate noise-tolerance hearing test system for astronauts. The device includes Bekesy-like threshold audiometry, distortion product otoacoustic emission...