Health, Medicine, & Biotechnology

Briefs : Medical
Bayesian Sleep Fusion

To ensure mission success, astronauts must maintain a high level of performance, even when work-rest schedules result in chronic sleep restriction and circadian misalignment, both of which can contribute to fatigue and performance deficits unless effective countermeasures are used. The overarching goal of this project is to...

Briefs : Medical
Technique for Reversible Permeabilization of Live Cells for Intracellular Delivery of Quantum Dots

Nanomaterials are comparable in size to various biomolecules (1 to 100 nm), and have unique properties such as enhanced electrical conductivity, increased chemical reactivity, and novel optical properties that make them attractive candidates for...

Briefs : Medical
Introduction of Structural Affinity Handles as a Tool in Selective Nucleic Separations

This invention relates to the general field of bio-chemical separations. Current methods for separating nucleic acids either lack sufficient selectivity or large-capacity production as required for gene therapy or DNA vaccines or other applications. There is a...

Briefs : Medical
Functionalized Patterning of Tissue Engineering Substrates

Tissue engineering (TE) is an emerging field for tissue repair and regeneration compared to conventional techniques including autograft and allograft, through engineering functional implants created from living cells. TE is a highly interdisciplinary research area where material science,...

Briefs : Medical
Hearing Test System Suitable for Self-Administered Hearing Assessment

Astronauts have developed hearing loss in space, so the goal of this project was to provide a robust, self-administered, accurate noise-tolerance hearing test system for astronauts. The device includes Bekesy-like threshold audiometry, distortion product otoacoustic emission...

Briefs : Medical
Assessment of Microbial Bioburden Within Aerogel Matrices

A makeshift apparatus has been designed composed of a sealed, hydrophobic 2-propanol/SiO2 aerogel component to filter outside air particles. Following verification and assessment, the apparatus was crafted with a Buchner funnel. Aerogel matrices were tightly fitted into filter...

Briefs : Medical
Universal Cell-Directed Nanotheranostics

The present invention relates to the field of nanotechnology and, more particularly, to the field of delivery of active agents such as therapeutic and/or imaging agents using micro/nanoscale particles. Porous particles, such as porous silicon particles and porous silica particles, have a number of...

Briefs : Medical
Fluid Preservation System (FPS)

Biological samples contain labile molecules that deteriorate rapidly ex-vivo. Terrestrially, biological samples are preserved either by freezing them (–80 °C) or by including preservation chemicals. While chemical preservation may be ideal for certain molecules, their functionality is selective and can, while...

Briefs : Medical
Using Electromagnetic Time-Variance Magnetic Fields to Generate and Re-Grow Cartilage

Adevice provides electromagnetic pulses at a predetermined frequency that will result in cartilage cell regeneration and regrowth for patients with arthritis, which reduces or eliminates joint cartilage. The device can be wrapped around the joints in a patient...

Briefs : Medical
Computer-Aided Design Tools to Support Human Factors Design Teams

The purpose of this work was to develop a database of human model behavior primitives, which are basic scripts that can be chained together to create simulations of humans performing certain tasks. This is unique in that the human model behaviors were collected using motion...

Briefs : Medical
Advanced-Capabilities Medical Suction Device

NASA has long recognized the difficulty in providing emergency medical care to astronauts in space. Many aspects of space travel make medical care inherently difficult, and sufficient storage space for medical equipment severely limits the ability to carry a full complement of diagnostic and...

Briefs : Medical
Use of Osteoclast-Inhibiting Compounds to Prevent Radiation-Induced Bone Loss

This technology features a method for preventing or treating radiation-associated loss of bone mass, bone density, or bone strength in a subject. This technology involves administering to the subject an amount of anti-resorptive or osteoclast-inhibiting compound...

Briefs : Medical
Polymerase Chain Reaction Preparation Kit and Self-Enclosed, Pipette-Free DNA/RNA Isolation Device

The ability to monitor and detect microorganism contamination/infection is important for long space voyages, in order to maintain a clean environment not only for the health of the astronauts, but also for electronics and structural materials....

Briefs : Medical
Hydrostatic Hyperbaric Oxygen Treatment Chamber

A hyperbaric chamber has been designed to achieve the goals of maximizing safety, minimizing complexity, and minimizing cost of hyperbaric chamber therapy. This design minimizes the volume of compressed gas in the chamber, and eliminates the need for complex gas mixing, carbon dioxide scrubbing,...

Briefs : Medical
Reagent and Method of Using a Microfluidic Cytometer for Leukocyte Differential Count

Leukocytes respond to toxic, infectious, and inflammatory processes to defend tissues and eliminate disease process or toxic challenge. Accurate and prompt counting and differentiation of leukocytes is critical for diagnoses of infection, leukemia, or allergy;...

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