Health, Medicine, & Biotechnology

Briefs : Medical
Bayesian Sleep Fusion

To ensure mission success, astronauts must maintain a high level of performance, even when work-rest schedules result in chronic sleep restriction and circadian misalignment, both of which can contribute to fatigue and performance deficits unless effective countermeasures are used. The overarching goal of this project is to...

Briefs : Medical
Technique for Reversible Permeabilization of Live Cells for Intracellular Delivery of Quantum Dots

Nanomaterials are comparable in size to various biomolecules (1 to 100 nm), and have unique properties such as enhanced electrical conductivity, increased chemical reactivity, and novel optical properties that make them attractive candidates for...

Briefs : Medical
Introduction of Structural Affinity Handles as a Tool in Selective Nucleic Separations

This invention relates to the general field of bio-chemical separations. Current methods for separating nucleic acids either lack sufficient selectivity or large-capacity production as required for gene therapy or DNA vaccines or other applications. There is a...

Briefs : Medical
Functionalized Patterning of Tissue Engineering Substrates

Tissue engineering (TE) is an emerging field for tissue repair and regeneration compared to conventional techniques including autograft and allograft, through engineering functional implants created from living cells. TE is a highly interdisciplinary research area where material science,...

Briefs : Medical
Hearing Test System Suitable for Self-Administered Hearing Assessment

Astronauts have developed hearing loss in space, so the goal of this project was to provide a robust, self-administered, accurate noise-tolerance hearing test system for astronauts. The device includes Bekesy-like threshold audiometry, distortion product otoacoustic emission...

Briefs : Medical
Assessment of Microbial Bioburden Within Aerogel Matrices

A makeshift apparatus has been designed composed of a sealed, hydrophobic 2-propanol/SiO2 aerogel component to filter outside air particles. Following verification and assessment, the apparatus was crafted with a Buchner funnel. Aerogel matrices were tightly fitted into filter...

Briefs : Medical
Using Electromagnetic Time-Variance Magnetic Fields to Generate and Re-Grow Cartilage

Adevice provides electromagnetic pulses at a predetermined frequency that will result in cartilage cell regeneration and regrowth for patients with arthritis, which reduces or eliminates joint cartilage. The device can be wrapped around the joints in a patient...

Briefs : Medical
Polymerase Chain Reaction Preparation Kit and Self-Enclosed, Pipette-Free DNA/RNA Isolation Device

Other applications include situations involving the military and in cases where one has to perform PCR analysis in the field.

The ability to monitor and detect microorganism contamination/infection is important for long space voyages, in...

Briefs : Medical
Hydrostatic Hyperbaric Oxygen Treatment Chamber

This system allows treatment of patients in remote locations.

A hyperbaric chamber has been designed to achieve the goals of maximizing safety, minimizing complexity, and minimizing cost of hyperbaric chamber therapy. This design minimizes the volume of compressed gas in the chamber, and...

Briefs : Medical
Reagent and Method of Using a Microfluidic Cytometer for Leukocyte Differential Count

The requirement for dilution is completely eliminated by specifically staining leukocytes.

Leukocytes respond to toxic, infectious, and inflammatory processes to defend tissues and eliminate disease process or toxic challenge. Accurate and prompt...

Briefs : Medical
Team Game and Simulation Control

This technology is an offshoot of LaRC-developed technologies using physiological measures for assessing pilot stress, sustained attention, engagement, and awareness in a laboratory flight simulation environment. The technology allows modulation of player inputs to a video game or simulation from a user interface...

Briefs : Medical
CRP Aptamers to Bone-Specific Alkaline Phosphatase (BAP)

In order to detect and quantify bone-specific alkaline phosphatase (BAP) in a human biological sample, a binding agent (molecule) that specifically recognizes BAP in a sample is typically required. This binding agent can then be used in numerous assays/instruments to enable the detection...

Briefs : Photonics/Optics
Low Er-Doped Yttrium Gallium Garnet (YGG) as Active Media for Solid-State Lasers at 1651 nm

The typical approach for producing laser output at the 1651-nm wavelength is via nonlinear frequency conversion. Lasers based on nonlinear conversion are complex, and it is very difficult to provide stability over time and over a wide range of operating...

Briefs : Sensors/Data Acquisition
Signal Processing Software for Remote Vital Sign Monitoring

This software provides the processing for a non-contact system that remotely estimates the heart rate and respiration rate of individuals as they carry on daily activities, and also enables detection of heart and respiration rate through walls.

Briefs : Sensors/Data Acquisition
Detecting High Stress in Oral Interviews and Text Documents

Content of an interview or text is subjected to various levels of statistical analysis to determine if the person knows the truth and is communicating it.

When a person is interviewed, some of the answers may be inaccurate, or even deceptive, because the person may have either...

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