Topics

Health, Medicine, & Biotechnology

Briefs : Medical
Fluorescence-Activated Cell Sorting of Live Versus Dead Bacterial Cells and Spores

This innovation is a coupled fluorescence-activated cell sorting (FACS) and fluorescent staining technology for purifying (removing cells from sampling matrices), separating (based on size, density, morphology, and live versus dead), and concentrating cells...

Briefs : Medical
Nonhazardous Urine Pretreatment Method

A method combines solid phase acidification with two non-toxic biocides to prevent ammonia volatilization and microbial proliferation. The safe, nonoxidizing biocide combination consists of a quaternary amine and a food preservative. This combination has exhibited excellent stabilization of both acidified...

Briefs : Medical
Method and Apparatus for Automated Isolation of Nucleic Acids from Small Cell Samples

RNA isolation is a ubiquitous need, driven by current emphasis on microarrays and miniaturization. With commercial systems requiring 100,000 to 1,000,000 cells for successful isolation, there is a growing need for a small-footprint, easy-to-use device that can...

Briefs : Medical
Flexible Sensors Offer View into Epileptic Seizures

Tapping into the human brain to understand its functions in daily life — as well as its malfunctions in illness — has long been a challenge for researchers. Mapping brain activity requires unwieldy, invasive arrays of electrodes and sensors that can damage tissue while only reading activity...

Briefs : Materials
Biosensor May Improve Disease Detection

A quick, inexpensive and highly sensitive test that identifies disease markers or other molecules in low-concentration solutions could be the result of a Cornell-developed nanomechanical biosensor, which could potentially help with early stage disease detection.

Briefs : Photonics/Optics
Fingertip-Sized Microscope to Study the Brain and its Diseases

A readily portable miniature microscope weighing less than 2 grams and tiny enough to balance on your fingertip has been developed. The scope is designed to see fluorescent markers, such as dyes, commonly used by medical and biological researchers studying the brains of mice.

Briefs : Medical
Beat-to-Beat Blood Pressure Monitor

This device provides non-invasive beat-to-beat blood pressure measurements and can be worn over the upper arm for prolonged durations. Phase and waveform analyses are performed on filtered proximal and distal photoplethysmographic (PPG) waveforms obtained from the brachial artery. The phase analysis is used...

Briefs : Medical
Developing Physiologic Models for Emergency Medical Procedures Under Microgravity

Several technological enhancements have been made to METI’s commercial Emergency Care Simulator (ECS) with regard to how microgravity affects human physiology. The ECS uses both a software only lung simulation, and an integrated mannequin lung that uses a...

Briefs : Medical
Improving Balance Function Using Low Levels of Electrical Stimulation of the Balance Organs

Crewmembers returning from long duration space flight face significant challenges due to the microgravity induced inappropriate adaptations in balance/sensorimotor function. The Neuroscience Laboratory at JSC is developing a method based on stochastic...

Briefs : Medical
Hands-Free Transcranial Color Doppler Probe

Current transcranial color Doppler (TCD) transducer probes are bulky and difficult to move in tiny increments to search and optimize TCD signals. This invention provides miniature motions of a TCD transducer probe to optimize TCD signals.

Briefs : Medical
Portable Intravenous Fluid Production Device for Ground Use

There are several medical conditions that require intravenous (IV) fluids. Limitations of mass, volume, storage space, shelf-life, transportation, and local resources can restrict the availability of such important fluids. These limitations are expected in long-duration space...

Briefs : Medical
Adaptation of a Filter Assembly to Assess Microbial Bioburden of Pressurant Within a Propulsion System

A report describes an adaptation of a filter assembly to enable it to be used to filter out microorganisms from a propulsion system. The filter assembly has previously been used for particulates >2 μm. Projects that utilize large volumes of...

Briefs : Medical
PMA-Linked Fluorescence for Rapid Detection of Viable Bacterial Endospores

The most common approach for assessing the abundance of viable bacterial endospores is the culture-based plating method. However, culture-based approaches are heavily biased and oftentimes incompatible with upstream sample processing strategies, which make viable...

Briefs : Manufacturing & Prototyping
Pre-Validated Medical Packaging Solution

Due to the complex requirements of the medical device industry, the internal resources of device OEMs are drawn primarily to the device R&D and regulatory arenas. However, once the device R&D is complete, there is still a major hurdle left to tackle: how to get a product into a validated sterile barrier...

Briefs : Medical
Silk Microneedles Deliver Controlled-Release Drugs Painlessly

Bioengineers have developed a new silk-based microneedle system able to deliver precise amounts of drugs over time and without need for refrigeration. The tiny needles can be fabricated under normal temperature and pressure and from water, so they can be loaded with sensitive...

Question of the Week
Which Superpower Do You Want Most?

Webcasts

Technology Leaders