Printing Life: Fully Biologic Organ-on-Chip Tissues That Could Heal

FRESH 3D bioprinting can now create fully biologic, collagen-based organ-on-chip systems with fine vascular channels, mimicking real human tissue. These constructs support better cell adhesion and remodeling than traditional devices and enable realistic disease models—including pancreatic-like tissue with potential for Type 1 diabetes therapy. Beyond modeling, the platform allows tissues to mature toward implantable function, marking a shift toward printing designs that self-organize into clinically meaningful human tissues, powered by multidisciplinary, team-based science.