Researchers from Boston University School of Medicine (BUSM) have estimated that one in six women are at risk for developing Alzheimer’s disease in their lifetime, while the risk for men is one in ten. According to the researchers, the greater lifetime expectancy for women translates into a greater lifetime risk of several diseases.
The researchers followed 2,794 participants in the Framingham Heart Study for 29 years who were without dementia. They found 400 cases of dementia of all types and 292 cases of Alzheimer’s disease. They estimated the lifetime risk of any dementia at more than one in five for women, and one in seven for men. Stroke and dementia are the most widely feared, age-related, neurological diseases, and are also the only neurological disorders listed in the ten leading causes of disease burden.
“The realization that the lifetime risk of stroke or dementia was more than one in three in both sexes, which is higher than the lifetime risk of coronary heart disease in women, is sobering,†said lead author Sudha Seshadri, MD, an associate professor of neurology at Boston University School of Medicine and an investigator of the Framingham Heart Study. “People should be aware of the risk of a disease at some point in their life. Similarly, such statistics are essential for public health planners to estimate the projected disease burden in a population during its expected lifespan,†she added.
